Introduction: Leptin, secreted from adipose tissue may have some correlation with coronary artery disease according to some reports in literature. The mean concentration of plasma leptin in patients with normal and abnormal myocardial perfusion imaging (MPI) and relation of leptin levels, independently to abnormality in MPI after correction for body mass index (BMI) was evaluated. Methods...

Over the past 20 years, SPECT myocardial perfusion imaging (MPI) has become an important tool for assessing patients with known or suspected coronary artery disease (CAD). Despite the success of SPECT MPI, laboratories that are performing these procedures are under pressure to reduce costs, improve image acquisition efficiency, reduce absorbed radiation dose, and improve diagnostic accuracy. Ph...

BACKGROUND Color tissue Doppler imaging M-mode through the mitral leaflet is an easy and precise method to estimate all cardiac time intervals from 1 cardiac cycle and thereby obtain the myocardial performance index (MPI). However, the prognostic value of the cardiac time intervals and the MPI assessed by color tissue Doppler imaging M-mode through the mitral leaflet in patients with ST-segment...

Purpose: Magnetic hyperthermia treatment (MHT) is a strategy for cancer therapy using the temperature rise of magnetic nanoparticles (MNPs) under an alternating magnetic field (AMF). Recently, a new imaging method called magnetic particle imaging (MPI) has been introduced. MPI allows imaging of the spatial distribution of MNPs. The purpose of this study was to investigate the feasibility of vis...

Introduction Magnetic particle imaging (MPI) is a new tomographic imaging modality that directly and quantitatively images the concentration of iron oxide nanoparticles without anatomical background signal [1]. It combines high sensitivity [2,3] with the ability of fast volumetric imaging. Recently, 3D real-time MPI of the blood flow through the heart and lung of mice has been demonstrated [4] ...

INTRODUCTION The clinical feasibility of noninvasive imaging of interstitial alterations after myocardial infarction (MI) was assessed using a technetium-99m-labeled RGD imaging peptide (RIP). In experimental studies, RIP has been shown to target integrins associated with collagen-producing myofibroblasts (MFB). METHODS AND RESULTS Ten patients underwent myocardial perfusion imaging (MPI) wit...

BACKGROUND It remains unclear whether myocardial contrast echocardiography (MCE) is as accurate as myocardial perfusion imaging with technetium-99m sestamibi (MPI) for the diagnosis of acute coronary syndrome (ACS). We sought to directly compare the diagnostic accuracy of MCE with resting MPI in a head-to-head fashion. METHODS We prospectively enrolled 98 consecutive patients (mean age; 59+/-...

Magnetic particle imaging (MPI) is a non-invasive imaging modality for direct detection of superparamagnetic iron-oxide nanoparticles based on the nonlinear magnetization response of magnetic materials to alternating magnetic fields. This highly sensitive and rapid method allows both a quantitative and a qualitative analysis of the measured signal. Since the first publication of MPI in 2005 sev...

OBJECTIVES The purpose of this study was to evaluate the prognostic value of community-based myocardial perfusion imaging (MPI) and to assess the incremental value of individual components of (99m)Tc-sestamibi single photon emission computed tomography (SPECT). BACKGROUND Although the most rapid growth of MPI has been in community outpatient laboratories, its prognostic value has not been val...

Introduction: One of the most important causes of death in patients with end-stage renal disease (ESRD) and even after kidney transplantation is cardiovascular diseases. Thus, cardiac evaluation is of utmost importance in the management of these patients especially during preoperative work up before renal transplantation. The aim of present study is to evaluate the role of myoc...