BACKGROUND Information is limited regarding the multifunctional role of GnRH agonist (GnRHa) therapy in reproductive diseases. We investigated the pattern of changes in inflammatory reaction, micro-vessel density and apoptosis in the tissues collected from women with endometriosis, adenomyosis and uterine myoma who were treated with or without GnRHa therapy. METHODS Biopsy specimens were coll...

In order to determine the occurrence of endometriosis in patients with uterine myoma and in those with polycystic ovarian disease (PCOD) compared to controls, 540 infertile patients were fIrst divided into two age groups of 20-29 and 30-39. Then each group was subdivided to patients with 1) uterine myoma, 2) PCOD, and 3) no uterine myoma or PCOD (control subgroup). The occurrence of endomet...

BACKGROUND Laparoscopic bipolar coagulation of uterine vessels (LBCUV) has been employed for women with symptomatic uterine myomas, but its effect on subsequent pregnancy has not been characterized. METHODS Four-hundred and twenty-three women entered the study between March 1999 and December 2001. Of these, 142 women (33.6%) were under the age of 40 years at the time of LBCUV, 36 of whom (36/...

BACKGROUND We recently demonstrated the effect of gonadotrophin-releasing hormone agonist (GnRHa) on tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma. Here, we investigated expression of GnRH receptors (GnRHRs) and effect of GnRHa on the proliferation of cells derived from endometria and pathological lesions of women with these reproductive disease...

background: leiomyomas are the most common benign tumors of the uterus. removal of the prolapsed pedunculated submucous myoma represents a distinct entity. evaluation and treatment of such cases may need intervention via the hymen.mini-laparotomic management of a pedunculated submucous myoma while preserving hymen integrity in a virginal patient is described as a safe alternative.. case: a 30-y...

in order to determine the occurrence of endometriosis in patients with uterine myoma and in those with polycystic ovarian disease (pcod) compared to controls, 540 infertile patients were first divided into two age groups of 20-29 and 30-39. then each group was subdivided to patients with 1) uterine myoma, 2) pcod, and 3) no uterine myoma or pcod (control subgroup). the occurrence of endometrios...

BACKGROUND The association between uterine myoma and infertility is still controversial. The anatomical defect of endometrium by uterine fibroids could be a factor for reducing pregnancy rates and increasing miscarriage rates. However, pregnancy and implantation rates were found to be significantly lower in women with intramural myomas (IMMs), when there was no deformity of uterine cavity. This...