Objective(s): This study was performed to investigate the effects of mucosal acidification on mRNA expression and protein synthesis of cystathionine gamma lyase (CSE), cystathionine beta synthase (CBS), and mucosal release of H2S in gastric mucosa in rats. Materials and Methods:Thirty-two rats were randomly assigned into 4 groups (8 in each), including: the control group, HCl (10 mM) treated g...

We present a fully defined culture system (adapted Essential8TM [E8TM ] medium in combination with vitronectin) for human embryonic stem cells that can be used for SILAC purposes. Although a complete incorporation of the labels was observed after 4 days in culture, over 90% of precursors showed at least 10% conversion. To reduce this arginine conversion, E8TM medium was modified by adding (1) l...

We study the performance of DPLL algorithms on parameterized problems. In particular, we investigate how difficult it is to decide whether small solutions exist for satisfiability and other combinatorial problems. For this purpose we develop a Prover-Delayer game which models the running time of DPLL procedures and we establish an information-theoretic method to obtain lower bounds to the runni...

The effect of ellagic acid on oxidative stress and hypertension induced by Nω-Nitro-L-arginine methyl ester hydrochloride (L-NAME) was investigated. Male Sprague-Dawley rats were administrated with L-NAME (40 mg/kg/day) for five weeks. L-NAME induced high systolic blood pressure (SBP) and increased heart rate (HR), hindlimb vascular resistance (HVR) and oxidative stress. Concurrent treatment wi...

In the framework of the SU(3) chiral quark model, the S−wave baryon-baryon bound states are investigated. It is found that according to the symmetry character of the system and the contributions from chiral fields, there are three types of bound states. The states of the first type, such as [ΩΩ] (0,0) and [Ξ * Ω] (0,1/2) are deeply bound dibaryon with narrow widths. The second type states, [Σ *...

We show that for every large enough integer N, there exists an N-point subset of L1 such that for every D > 1, embedding it into `d 1 with distortion D requires dimension d at least NΩ(1/D ), and that for every ε > 0 and large enough integer N, there exists an N-point subset of L1 such that embedding it into `d 1 with distortion 1 + ε requires dimension d at least N1−O(1/ log(1/ε)). These resul...

We show that if gap-3SAT has no sub-exponential time algorithms then a weak form of the sliding scale conjecture holds. Namely, for every α > 0 any algorithm for nα-approximating the value of label cover must run in time at least nΩ(exp(1/α)), where n is the size of the instance. Put differently, if there is a polynomial time algorithm for approximating the value of label cover to within a fact...

We apply the theory of markov random fields on trees to derive a phase transition in the number of samples needed in order to reconstruct phylogenies. We consider the Cavender-Farris-Neyman model of evolution on trees, where all the inner nodes have degree at least 3, and the net transition on each edge is bounded by ǫ. Motivated by a conjecture by M. Steel, we show that if 2(1 − 2ǫ)2 > 1, then...

Metabolism of the amino acid L-arginine is implicated in many physiological and pathophysiological processes including autoimmune conditions such as type 1 diabetes (T1D). Alternate arginine metabolism through the citrulline-nitric oxide (NO) or the ornithine pathways can lead to proinflammatory or immune regulatory effects, respectively. In this report, we blocked the arginine-ornithine metabo...

The Frieze-Kannan regularity lemma is a powerful tool in combinatorics. It has also found applications in the design of approximation algorithms and recently in the design of fast combinatorial algorithms for boolean matrix multiplication. The algorithmic applications of this lemma require one to efficiently construct a partition satisfying the conditions of the lemma. Williams [25] recently as...