OBJECTIVE To examine the performance of chromosome-selective sequencing of cell-free (cf) DNA in maternal blood for assessment of fetal sex chromosome aneuploidies. METHODS This was a case-control study of 177 stored maternal plasma samples, obtained before fetal karyotyping at 11-13 weeks of gestation, from 59 singleton pregnancies with fetal sex chromosome aneuploidies (45,X, n = 49; 47,XXX...

A fabrication method of linkers to covalently anchor nucleic acid probes (such as, oligonucleotides, PCR-products or peptide nucleic acid oligomers) on glass was developed by alternatively covalently assembling the different molecular components. The linkers with controllable length, flexibility and hydrophilicity could be prepared simply by dipping subtracts alternatively in different chemical...

Mucosal Immunology. http://dx.doi.org/10.1016/B978-0-12-415847-4.00059-8 2015 Published by Elsevier Inc. Chapter Outline Introduction 1129 Virology 1130 Paramyxoviruses 1130 Influenza Viruses 1130 Coronaviruses and Rhinoviruses 1131 Adenoviruses 1131 Clinical Features and Epidemiology 1131 RSV 1132 HPIV 1132 HMPV 1132 Influenza Viruses 1133 Coronaviruses 1133 Rhinoviruses 1134 Adenoviruses 1134...

Aflatoxins, metabolites of the fungus Aspergillus flavus, are potent liver toxins and carcinogens in animals, and may also be human carcinogens. Although aflatoxin contamination in corn is uncommon in Kentucky, occasional incidents do occur and can create significant economic losses for individual producers. Of all the known mycotoxins (toxic substances produced by fungi), aflatoxins in corn an...

Oxidant/antioxidant imbalance has been reported in some infectious diseases, including community-acquired pneumonia (CAP). The aim was to assess the antioxidant status in adults with CAP and its relationship with clinical severity at admission. Fifty-nine patients with CAP were enrolled and categorized at admission by the FINE score, from July 2010 to October 2012. In the same period 61 control...

The stability of phases at finite temperatures is given by the free energy. But the fact that it is not expressible in terms of ensemble averages over functions of position and velocity coordinates, complicates its determination in atomistic simulations. In order to overcome this problem, thermodynamic integration methods are used. This method is not limited to thermodynamic paths which can be ...

The article presents the results of study aeropalinological spectra city Cherepovets (59 ° 07′59 ″ N, 37 53′59 E), carried out during growing season 2014-2015. method gravimetric sampling was used (Durham’s pollen trap). Data obtained on 22 taxa and dynamics dusting various palynomorphs; dominant palinospectrum were identified, as well non-pollen palynomorphs in air. It is shown that Betula gra...