Regulation of intracellular sodium ion concentration ([Na]i) is critical for nervous system function, not only because sodium ions are the major current carriers during action potentials and excitatory postsynaptic currents in neurones, but also because many other cellular functions (e.g. intracellular Ca2+ homeostasis, intracellular pH homeostasis, reuptake of transmitters) are directly depend...

The role of Na+-H+ exchange in Na+ transport across the apical membrane was evaluated in Necturus gallbladder epithelium by means of intracellular Na+ activity (aNai) and 22Na+ uptake measurements. Under control conditions, complete replacement of Na+ in the mucosal solution with tetramethylammonium reduced aNai from 14.0 to 6.9 mM in 2 min (P less than 0.001). Mucosal addition of the Na+-H+ ex...

salt stress is one of the most chalanging abiotic stresses affecting natural productivity and causing significant croplosses worldwide. a greenhouse experiment was conducted to evaluate the response of two alfalfa cultivars (bamiand hamedani) to 6 levels of salinity (0 as control, 25, 50, 75, 100, 125 mm nacl) at the college of agriculture,shiraz university, shiraz, iran in 2008. plant dry weig...

background : the aim of the current study was to develop a marking technique as an internal marker to mark post blood meal mosquitoes by using stable phosphate isotope 32 p and determine the optimal concentration of it. methods : an isotonic physiological saline solution, containing different concentration of radioactive isotope 32 p-labeled disodium phosphate (na 2 h 32 po4) was injected into ...

Inhibition by cardiac glycosides of Na(+), K(+)-ATPase reduces sodium efflux from myocytes and may lead to Na(+) and Ca(2+) overload and detrimental effects on mechanical function, energy metabolism, and electrical activity. We hypothesized that inhibition of sodium persistent inward current (late I(Na)) would reduce ouabain's effect to cause cellular Na(+) loading and its detrimental metabolic...

background: due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. however, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. so, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent’s child...

the control of biological, hydrological and geochemical cycles of soil is the key part of the earth system. the objective of this research was to evaluate changes in soil chemical properties due to deforestation occurred in the gazafolya village, merek watershed, kermanshah province, iran. toward this attempt, 35 soil samples were collected from top soil layer using auger in early june, 2013. s...

The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalyti...

Geoffrey Davenport, Ian McDonald and Caroline Moss-Gibbons, The Royal College of Physicians and its collections: an illustrated history, London, Royal College of Physicians, 2001, pp. 168, illus., UK £38.00, overseas £45.00 (hardback 0-907-383-831). Michael Dunnill, The Plato of Praed Street: the life and times of Almroth Wright, London, Royal Society of Medicine Press, 2000, pp. xiii, 269, ill...