We report label-free detection of single mitochondria with high sensitivity using nanoelectrodes. Measurements of the conductance of carbon nanotube transistors show discrete changes of conductance as individual mitochondria flow over the nanoelectrodes in a microfluidic channel. Altering the bioenergetic state of the mitochondria by adding metabolites to the flow buffer induces changes in the ...

The ability to measure extremely low thrust levels with unusual precision is becoming more critical as attempts are made to characterize the performance of emerging micropropulsion systems. Many new attitude control concepts for nanospacecraft involve the production of thrust below 1 μN. A simple, but uniquely successful thrust stand has been developed and used to measure thrust levels as low a...

Exploring the reactivity of metal clusters is an important task in cluster science, while only a few previous studies involve the reactions of nano-sized ones. Here we report a kinetic measurement on reactions of Ag(n)(-) (n = 6-69) with O2 using a flow reactor running at 120 K. Their relative rates were obtained by fitting decay processes of parent ions at different O2 flow rates. Comparing th...

A hybrid atomistic-continuum method devoted to the study of multi-scale problems is presented. The simulation domain is decomposed into three regions: the bulk where the continuous Navier-Stokes and energy equations are solved, the neighbourhood of the wall simulated by the Molecular Dynamics and the overlap region which connects the macroscopic variables (velocity and temperature) between the ...

This paper reviews the fundamentals of micropolar fluid dynamics (MFD), and proposes a numerical scheme integrating Chorin’s projection method and time-centred split method (TCSM) for solving unsteady forms of MFD equations. It has been known that Navier–Stokes equations are incapable of explaining the phenomena at micro and nano scales. On the contrary, MFD can naturally pick up the physical p...

Nanoparticle self-assembly is a complex phenomenon, the control of which is complicated by the lack of appropriate tools and techniques for monitoring the phenomenon with adequate resolution in real-time. In this work, a label-free technique based on dark-field microscopy was developed to investigate the self-assembly of nanoparticles. A bio-nanoparticle with complex shape (T4 bacteriophage) th...

PURPOSE The normal metabolite methylglyoxal (MG) specifically kills cancer cells by inhibiting glycolysis and mitochondrial respiration without much adverse effect upon normal cells. Though the anticancer property of MG is well documented, its gradual enzymatic degradation in vivo has prompted interest in developing a nanoparticulate drug delivery system to protect it and also to enhance its ef...

in this study, the effect of nano-silver (ag) treatment on the drying rate and final moisture gradient of poplar wood was investigated. poplar (populous nigra) boards with green dimensions of 100×70×50 and 20 mm were treated with nano-silver (ag) suspension by spraying and immersion method. two concentrations of nano-silver suspension, including 20 and 100 ppm were used. then, the boards were c...

Using nano-technology materials in the asphalt pavement industry is new compared with Portland cement concrete. The main objective of this study is to investigate the effects of nano-silica modification on some properties of a penetration grade asphalt cement and a typical asphalt concrete. 60/70 penetration grade bitumen was modified with different percentages of nano-silica (i.e. 1, 3 and 5%,...

Titanium thin layers with the same deposition conditions were deposited on glass substrates at room temperature. Different annealing temperatures namely, 400 K, 500 K and 600 K with uniform 9 cm /sec oxygen 3 flow were used to produce titanium oxide layers. The nano-structure of layers were studied using AFM and XRD methods. Optical Reflectance were studied by spectrophotometer method. Correlat...