The naphthalene dioxygenase (NDO) system catalyzes the first step in the degradation of naphthalene by Pseudomonas sp. strain NCIB 9816-4. The enzyme has a broad substrate range and catalyzes several types of reactions including cis-dihydroxylation, monooxygenation, and desaturation. Substitution of valine or leucine at Phe-352 near the active site iron in the alpha subunit of NDO altered the s...

The asymmetric unit of the title compound, C(24)H(22)O(4), contains two independent mol-ecules in both of which the naphthalene ring systems adopts a transoid arrangement. The dihedral angles between the naphthalene ring system in the two mol-ecules are 83.0 (1) and 89.0 (1)°. There are slight differences in the C(H(3))-O-C(H(2))-O- torsion angles of the eqivalent meth-oxy-meth-oxy groups. In t...

Naphthalene has been described as new class of potent antimicrobials against wide range of human pathogens. It occupies a central place among biologically active compounds owing to its varied and exciting antibiotic properties with less toxicity [1]. Numerous naphthalene containing antimicrobial drugs are existing like naftifine, nafacillin, terbinafine, tolnaftate, etc. that plays vital role a...

Cunninghamella elegans oxidized naphthalene to ethyl acetate-soluble and water-soluble metabolites. Experiments with [14C]-naphthalene indicated that 21% of the substrate was converted into metabolites. The ratio of organic-soluble metabolites to water-soluble metabolites was 76:24. The major ethyl acetate-soluble naphthalene metabolites were trans-1,2-dihydroxy-1,2-dihydro-naphthalene, 4-hydro...

The enzymes of naphthalene metabolism are induced in Pseudomonas putida ATCC 17484, PpG7, NCIB 9816, and PG and in Pseudomonas sp. ATCC 17483 during growth on naphthalene or salicylate; 2-aminobenzoate is a gratuitous inducer of these enzymes. The meta-pathway enzymes of catechol metabolism are induced in ATCC 17483 and PPG7 during growth on naphthalene or salicylate or during growth in the pre...

The title compound, C(25)H(22)Br(2)O(2), crystallizes with two mol-ecules in the asymmetric unit. In each independent mol-ecule, the two naphthalene ring systems are nearly perpendicular to one another, with dihedral angles of 85.6 (1) and 86.2 (1)°. The crystal structure is stabilized by C-H⋯π inter-actions, and inter- and intra-molecular C-H⋯O and C-H⋯Br hydrogen bonds.

In the title compound, C(30)H(21)As·CHCl(3), the dihedral angles between the three naphthalene ring systems [r.m.s. deviations = 0.007, 0.009 and 0.020 Å] are 72.54 (4), 88.05 (4) and 83.36 (4)°. In the crystal, the mol-ecules are stacked down the a axis being consolidated by C-H⋯π and π-π inter-actions [centroid to centroid distance = 3.7839 (7) Å].

The title compound, C(26)H(20), lies about an inversion centre. The naphthalene unit and the hexa-triene chain are each approximately planar (maximum deviations of 0.0143 and 0.0042 Å, respectively), and are inclined to one another at a dihedral angle of 49.20 (4)°. The dihedral angle between the two naphthalene ring systems of neighboring mol-ecules is 85.71 (4)°.