Resection of benign lesions is a common cause of nasal defects in young patients. The conventional bilobed flap (Zitelli’s design) used for reconstruction of defects of the lower third of the nose traditionally utilizes skin from the mid dorsum and the sidewall of the nose.[1] However, the conspicuous scarring and loss of conformity in the cosmetic subunits of the nose might be unacceptable to ...

dermatomyositis (dm) is a rare idiopathic inflammatory myopathy with characteristic skin lesions. case series have shown an association between dermatomyositis and malignancy. malignancy has been found in 15-25% of the adult patients with dermatomyositis. a 50-year-old new case of breast cancer, was admitted with muscle weakness and inability to walk. physical examination revealed fever, perior...

Figure 1. Diatoms in cytologic samples of Florida manatees (Trichechus manatus latirostris) in A, C, D, F, G, J–L, bottlenose dolphins (Tursiops truncatus) in B, E, I, and a seahorse (Hippocampus erectus) in H. Wright–Giemsa stain.9100 objective (except F;920). (A) naviculoid benthic diatom; skin contamination of urine sediment; wet mount. (B) Nitzschia sp.; gastric fluid direct smear. (C) Navi...

Proteoglycans comprise a family of complex macromolecules consisting of a core protein with covalently attached glycosaminoglycan (GAG) chains. The skin anti-aging effects of oral administration of proteoglycan fractions with different molecular weights from salmon nasal cartilage were investigated in a hairless mouse model of skin aging; aging wa...

BACKGROUND Double-blinded challenges are widely used for diagnosing food allergy but are time-consuming and cause severe reactions. Outcome relies on subjective interpretation of symptoms, which leads to variations in outcome between observers. Facial thermography combined with nasal peanut challenge was evaluated as a novel objective indicator of clinical allergy. METHODS Sixteen children wi...

BACKGROUND Repair of the rare median cleft lip occurring with agenesis of the columella is a challenge as there is a major deficiency of skin and underlying structures. MATERIAL AND METHODS Over a 23- year period, five children underwent construction of a columella. A new surgical technique was designed for this: an internal dorsal nasal flap was used to create a cutaneous-cartilaginous flap ...

INTRODUCTION Field studies for allergic rhinitis (AR) commonly have inconsistent allergen concentrations and subject exposure patterns due to varying environmental conditions and subject behaviors. A technical and clinical validation study was conducted for the Allergen BioCube® using timothy grass to confirm uniform allergen concentration and clinically relevant subject symptom responses. ME...