We report on the present state of commissioning of the cryogenic electrostatic trap for fast ion beams (CTF) at the Max-Planck-Institut für Kernphysik in Heidelberg. The device has recently passed a cryogenic test, during which the trap was cooled down by 1.8 K superfluid helium. No leaks of the helium supply system were observed, the temperature below 10 K was reached, and the required positio...

Using material already available in the operating room, we describe the construction and application of a percutaneous transtracheal needle insufflation device to be used in pediatric airway emergencies. Our technique of percutaneous needle insufflation using common materials found in the operating room can be a helpful adjunct in a time of need. Quickly constructed and at a minimal cost, the d...

Periconceptional folic acid (FA) reduces neural tube defect (NTD) risk, but seems to have a varying effect per NTD subtype. We aimed to study the effect of FA supplementation on NTD subtype distribution using data from EUROCAT Northern Netherlands. We included all birth types with non-syndromal NTDs born in 1997-2012. By Fisher's exact test we analyzed possible differences in NTD subtype distri...

RNA helicase A (RHA) undergoes nuclear translocation via a classical import mechanism utilizing karyopherin beta. The nuclear transport domain (NTD) of RHA is known to be necessary and sufficient for its bi-directional nuclear trafficking. We report here that arginine methylation is a novel requirement for NTD-mediated nuclear import. Nuclear translocation of glutathione S-transferase (GST)-NTD...

Figure 2: The robotic system developed for MR image-guided prostate biopsy and brachytherapy. The robot operates inside the bore during imaging, is registered to the scanner using a fiducial frame, and aligns the needle to targets selected in intraoperative MR imaging. The needle is inserted using a master device that lets the clinician stand beside the patient, view real-time MR images aligned...

We present the proof-of-concept prototype of a prostate biopsy robot to be used inside a conventional high-field MRI scanner. A three degree-offreedom (DOF) mechanical device translates and rotates inside the rectum and enters a needle into the body, and steers the needle to a target point pre-selected by the user. The device is guided by real-time images from the scanner. Networked computers p...

BACKGROUND Pain and needle-phobia can be a problem during the application of local anesthesia with syringe and needle. OBJECTIVE To evaluate a jet-injection device (without needle) to deliver local anesthesia. METHODS Two hundred and six minor dermatological procedures using a jet-injection device for administering local anesthesia into skin tissue were performed. We comment on the technica...

BACKGROUND Short-axis ultrasound-guided placement of central venous catheters (CVCs) is widely accepted as safe practice. However, utilizing the long-axis approach could further improve safety, as it allows for better visualization of the needle as it is advanced to the target vessel. However, the long-axis approach has not widely been used due to the technical difficulty. Recently, a new needl...

PURPOSE To evaluate the overall accuracy and time spent on biopsy guided by electromagnetic needle tracking in a phantom compared with the standard technique of US-guided biopsy with an attached steering device. Furthermore, to evaluate off-plane biopsy guided by needle tracking. MATERIALS AND METHODS Three different series of biopsy were performed in a phantom: one with a steering device att...

introduction: needle stick injuries (nsi) are major occupational hazards for health care workers. objectives: this study aimed to determine the epidemiology of needle sticks and sharp injuries among nurses of an iranian teaching hospital. materials and methods: this descriptive cross-sectional study was conducted in 2009 on 328 nurses in a health center in tehran. stratified random samples were...