Background: This study was targeted toward comparing volume-guaranteed (VG) ventilation with conventional pressure-controlled (PC) ventilation in preterm infants with respiratory distress syndrome (RDS) in terms of the facilitation of weaning and extubation and occurrence of complications, such as pneumothorax, intraventricular hemorrhage (IVH), retinopathy of prematur...

OBJECTIVES Assessing the value of the Combined-Apgar score in predicting neonatal mortality and morbidity compared to the Conventional-Apgar. METHODS This prospective cohort study evaluated 942 neonates (166 very preterm, 233 near term, and 543 term) admitted to a tertiary referral hospital. At 1- and 5-minutes after delivery, the Conventional and Combined Apgar scores were recorded. The neon...

Premature delivery, is always associated to the failure of respiratory transition and a delayed achievement of an adequate functional residual capacity. For this reason preterm babies (expecially the Extremely Low for Gestational Age -ELGAinfants) frequently need a respiratory support. Non-invasive ventilation (NIV) is widespread used in the management of respiratory distress even in ELGA infan...

introduction:guillain-barre syndrome(gbs) is the most common cause of acute flaccid paralysis. respiratory failure is the most serious short-term complication of gbs and invasive mechanical ventilation is required in 30% of patients.moreover,60% of those who are intubated develop major complications including pnemonia,sepsis,gi bleeding and pulmonary embolism. thus respiratory failure predictio...

background: ventilator-associated pneumonia (vap) is the most prevalent and lethal form of nosocomial infections in the icu and oral disinfection is a nursing measure to prevent this condition. aim: this study aimed to evaluate the effect of oronasal versus oral disinfections with chlorhexidine on the clinical criteria for diagnosis of vap. method: this randomized clinical trial was conducted o...

BACKGROUND The INtubation-SURfactant-Extubation (INSURE) is a procedure that is increasingly being used to treat the respiratory distress syndrome in preterm infants. The objective of this study was to identify predictors for an unsuccessful INSURE procedure. METHODS The neonates included were less than 32 weeks' gestation, treated with surfactant in the neonatal intensive care unit, and born...

Mechanical ventilation is the cornerstone of therapy for patients with acute respiratory distress syndrome (ARDS). Paradoxically, mechanical ventilation can exacerbate lung damage--a phenomenon known as ventilator-induced lung injury. While new ventilation strategies have reduced the mortality rate in patients with ARDS, this mortality rate still remains high. High-frequency oscillatory ventila...

BACKGROUND We examined the quality of the information on the use of surfactant and the use of and duration of nasal continuous positive airway pressure (nCPAP), oxygen supplementation, and mechanical ventilation in the Danish Neonatal Clinical Database (NeoBase). METHODS We included all neonates born with a gestational age < 32 weeks admitted to a Neonatal Intensive Care Unit (NICU) at two un...

Albertine KH. Utility of large-animal models of BPD: chronically ventilated preterm lambs. Am J Physiol Lung Cell Mol Physiol 308: L983–L1001, 2015. First published March 13, 2015; doi:10.1152/ajplung.00178.2014.—This paper is focused on unique insights provided by the preterm lamb physiological model of bronchopulmonary dysplasia (BPD). Connections are also made to insights provided by the for...

conclusions the results of this study indicated that pmv predictors could be specific for each center and a good administration program is needed for each pediatric cardiac surgery center for the preoperative management of patients undergoing congenital heart surgeries. results a total of 300 patients, 56.7% male, were enrolled in this study. their mean age was 32 ± 40 months .the median durati...