it is an autosomal recessive, and occasionally autosomal dominant mutant extremely rare disorder with only 100 reported case in literature. this fatal disorder occur in both sexes and all races. in most circumstances the newborn die soon after birth also it is known as harlequin fetus, alligator baby or keratosis diffusa fatalis. because of its rarity, we report 2 cases of this disorder, here.

background: in the recent decades, the prevalence of nosocomial infections in neonates has grown and almost 21% of preterm neonates experience these kinds of infections. some factors were proposed to have a protective effect against neonatal infections through promoting the development of the immune system of the newborn. this study aimed to evaluate the efficacy of oral glutamine supplementati...

meningitis, pneumonia, and sepsis in newborns and young infants (age < 60 days) are the main causes of childhood mortality in developing countries. even though streptococcus pneumonia is the most commonly detected microorganism in pediatric bacterial meningitis, it is rare in newborn infants. the following article reports a case of pneumococcal meningitis that was detected early in a newborn in...

the testicular torsion which is typically seen in prepuberty is very rare in the early neonatal period; prenatal diagnosis is difficult. herein, we report a five day-old male neonate with swelling and erythema of the right scrotum.  following doppler ultrasound suggestive of testicular torsion, surgical exploration was undertaken. there was gangrene of the right testis with discoloration and ne...

background: rooming-in, motivated by world health organization (who) strategies and baby-friendly hospital policies, is a practice followed in many maternity hospitals of iran. mother-infant dyad may easily be damaged by the separation caused by medical and surgical problems, which result in hospital stay. regarding this, the aim of this study was to investigate the effects of the rooming-in pr...

amikacin is a bactericidal aminoglycoside. aminoglycosides inhibit bacterial protein synthesis. the antibacterial spectrum of amikacin is the broadest of aminoglycosides. because of its resistance to many of the aminoglycosides-inactivating enzymes, it has a special role in hospitals where gentamicin- and tobramycin-resistant microorganisms are prevalent. amikacin is active against the majority...

This article explores the basic development and pathophysiology of the thyroid gland. New factors in the normal development of the thyroid in the neonate are mentioned. The incidence of congenital hypothyroidism continues to increase. We describe congenital hypothyroidism, its possible etiologies, treatment and outcomes. We explore hypothyroxinanemia in pre-term neonates and the risk/benefit of...

OBJECTIVE To present current guidelines regarding treatment of mastocytosis in pregnancy on the example of observed patients. DESIGN Case control national study. SETTING Polish Center of the European Competence Network on Mastocytosis (ECNM). POPULATION OR SAMPLE 23 singleton spontaneous pregnancies in 17 women diagnosed with mastocytosis in years 1999-2014, before becoming pregnant. ME...

We report the case of a neonate who likely developed symptoms of Neonatal Abstinence Syndrome after in-utero exposure to gabapentin for treatment of maternal chronic pain. The neonate developed symptoms of hypertonicity, tremor, and poor feeding twelve hours after delivery. Although the neonate wasbriefly exposed to the benzodiazepine alprazolam and the opioid oxycodone, the withdrawal symptoms...

Aim: To compare fetal and maternal outcomes between elective emergency cesarean sections in patients with gestational diabetes&#x0D; mellitus (GDM).&#x0D; Material Methods: Data from GDM delivered by section January 2015 July 2020 were&#x0D; retrospectively reviewed. Patients were grouped according to whether the was (n=129) or (n=158).&#x0D; Results: The rate higher (31.16%) than without GDM. ...