نتایج جستجو برای: neospora caninum
تعداد نتایج: 1677 فیلتر نتایج به سال:
background: the aim of this study was to determine the seroprevalence of antibody to neospora caninum in healthy and aborted dairy cattle in tabriz, capital of east-azarbaijan in northwest of iran. methods: in this cross-sectional study serum samples were collected from 266 healthy and aborted holestein-feriesisnc cows from september 2008 to august 2009. the sera were analyzed to detect of a...
Abstract Neospora caninum is an apicomplexan parasite that causes abortion in cattle, resulting significant economic losses. There no commercial treatment for neosporosis, and drug repositioning a fast strategy to test possible candidates against N. caninum. In this article, we describe the effects of atovaquone, chloroquine, quinine, primaquine tetracycline on proliferation. The IC50 concentra...
Recombinant Neospora caninum tachyzoite antigens were evaluated in an enzyme-linked immunosorbent assay (ELISA) for recognition by serum antibodies (Ab) from Neospora-infected cattle. Serum samples were obtained every 2 to 3 weeks for 8 to 15 months from 10 cows with histories of Neospora-associated abortion. Serum samples were also obtained from offspring of these animals and from a large numb...
El objetivo del estudio fue comparar las técnicas de inmunofluorescencia indirecta (IFI) y Enzimo inmunoensayo (ELISA) para el diagnóstico Neospora caninum Dubey, Carpenter, Speer, Topper Uggla, 1988 en alpacas la sierra Perú. Se evaluó sensibilidad, especificidad, valor predictivo positivo, negativo concordancia IFI usando referencia un kit comercial ELISA competitivo (cELISA - VMRD). obtuvier...
The in vitro effects of 19 dicationic diamidine derivatives against the proliferative tachyzoite stages of the apicomplexan parasites Neospora caninum and Toxoplasma gondii were investigated. Four compounds (DB811, DB786, DB750, and DB766) with similar structural properties exhibited profound inhibition of tachyzoite proliferation. The lowest 50% inhibitory concentrations were found for DB786 (...
Toxoplasma gondii is a zoonotic protozoan parasite which infects nearly one third of the human population and is found in an extraordinary range of vertebrate hosts. Its epidemiology depends heavily on horizontal transmission, especially between rodents and its definitive host, the cat. Neospora caninum is a recently discovered close relative of Toxoplasma, whose definitive host is the dog. Bot...
neospora caninum is an obligate intracellular parasitic protozoa and considered as causal agent of neosporosis which infect wide variety of hosts. ncgra7 is an immunodominant antigen recognized by sera from bovines, naturally infected by n. caninum, which is used as a powerful target for recombinant or dna vaccine preparation against neosporosis. there is no study about identifying the molecula...
Infection with Neospora caninum is regarded as a significant cause of abortion in cattle. Despite the economic impact of this infection, relatively little is known about the biology of this parasite. In this study, mini and microsatellite DNAs were detected in the genome of N. caninum and eight loci were identified that each contained repetitive DNA which was polymorphic among different isolate...
Cattle infected with Neospora caninum readily experience transplacental parasite transmission, presumably after maternal parasitemia, leading to abortion or birth of congenitally infected calves. Cytotoxic T lymphocytes (CTL) are important mediators of protective immunity against Toxoplasma gondii, an intracellular apicomplexan protozoan closely related to N. caninum. In this study, N. caninum-...
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