The essential oil composition of the aerial parts of Nepeta raphanorhiza is reported for the first time. Capillary GC-FID & GC-MS analysis of the essential oil led to the identification of 16 components accounting for 97.5% of the total oil. Sesquiterpene hydrocarbons dominated the oil composition accounting for 65.3 % followed by monoterpene hydrocarbons constituting 19.5 % of the total oil co...

Non-small cell lung cancer (NSCLC) is regarded as one of the major intractable diseases, which was cured mainly by chemotherapeutics in the clinical treatment at present. But it is still a vital mission for the current medical and researchers that hunting a natural medicine which have little side effects and high-efficiency against the NSCLC on account of the shortcomings on current drugs. Nepe...

In folklore medicine Drymaria Cordata willd (Fam:Caryophylaceae) is well known plant in Sikkim state, India. The present work summarizes preliminary phytochemical study of leaves of this plant.

Catnip (Nepeta cataria) is an important medicinal herb belonging to the mint family, Lamiaceae. In this study, the in vitro antimicrobial and antioxidant activities of the essential oil and methanol extract from Nepeta cataria, and its essential oil composition were investigated. The essential oil, which has 4aalpha,7alpha,7abeta-nepetalactone (70.4%), 4aalpha,7alpha,7abeta-nepetalactone (6.0%)...

Sparassis crispa (SC), known as Hanabiratake in Japanese, is an edible mushroom with various medicinal properties. We isolated 3 novel phthalides, designated hanabiratakelide A (1), B (2), and C (3), from the SC fruit body. In this investigation, 3 known phthalides (4-6), ubiquinone-9, and 2 known unsaturated fatty acids were also isolated. Their structures were elucidated primarily through ext...

Crispene E, a new clerodane-type diterpene, inhibited STAT3 dimerization in a cell-free fluorescent polarisation assay and was found to have significant toxicity against STAT3-dependent MDA-MB 231 breast cancer cell line and selectively inhibited the expression of STAT3 and STAT3 target genes cyclin D1, Fascin and bcl-2. Molecular docking studies suggest the molecule inhibits STAT3 by interacti...

Faced with critical shortages of staff, long queues, and stigma at public health facilities in Livingstone, Zambia, persons who suffer from HIV/AIDS-related diseases use medicinal plants to manage skin infections, diarrhoea, sexually transmitted infections, tuberculosis, cough, malaria, and oral infections. In all, 94 medicinal plant species were used to manage HIV/AIDS-related diseases. Most r...

Nepeta species are widely used in folk medicine as a diaphoretic, diuretic, antiseptic, astringent, anti-asthmatic, cough suppressant, antispasmodic, antipyretic, sedative and stomachic. This study was designed to examine the chemical composition of essential oil isaurica sulfuriflora. It determined that aerial parts N. plant contained 0.72% oil, 37 compounds were identified representing 98.86%...

Efektivitas pemberian beras basi sebagai pupuk organik selada merah menjadi topik yang sangat menarik untuk dibahas. Tujuan penelitian ini adalah menganalisis efektivitas padi pada tanaman ( Lactuca sativa var. Crispa). Parameter diamati dalam tinggi tanaman, jumlah daun dan pengendalian hama. Metode digunakan Rancangan Acak Kelompok (RAK) terdiri dari 3 perlakuan 1 kontrol dengan masing-masing...