Hereditary neuropathy with liability to pressure palsies (HNPP), an autosomal dominant disorder, is characterized by recurrent isolated nerve palsies, which are precipitated by trivial compression or trauma. In this report, we present the clinical features, electrophysiological studies, nerve biopsy results, and molecular analyses of a Taiwanese family. Among the 7 members evaluated, one latent...

Nerve biopsy is a valuable tool in the diagnostic work-up of peripheral neuropathies. Currently, major indications include interstitial pathologies such as suspected vasculitis and amyloidosis, atypical cases of inflammatory neuropathy and the differential diagnosis of hereditary neuropathies that cannot be specified otherwise. However, surgical removal of a piece of nerve causes a sensory defi...

Craniofacial skeletal metastasis is a rare presentation of advanced prostate cancer. This is a report of a 69-year-old man who presented with numbness of the right lower lip and recently ill-fitting lower denture. Based on the medical history of benign prostate hyperplasia (BPH) and suspicion of a metastatic tumor, prostate core needle biopsy was performed. Histology of the prostate biopsy con...

We report a diabetic patient who developed skin lesions on her left forearm and ulnar nerve involvement following admission to the hospital and putting IV catheter for her treatment. Biopsy samples wee taken from her skin lesions and ulnar nerve and with further evaluation after 2 months, the diagnosis of fungal infection due to zygomycetes and mucur was considered based on the presence o...

OBJECTIVES To evaluate the clinical, neurophysiological and histological features of cases of neuropathy developing after completion of anti-leprosy treatment, where biopsy showed inflammatory changes. PATIENTS AND METHODS Seven patients were evaluated by a single neurologist. Electro-neuro-myography and peripheral nerve biopsy were performed in all patients. RESULTS Median age was 50-6 yea...

a 16-years-old female patient with painless swelling of the right side of mandible is described. she noticed the swelling from two years ago, without painful symptoms. axial ct imaging showed buccal expansion with intact buccal and lingual cortical bone. the report of incisional biopsy was central odontogenic fibroma. under general anesthesia the lesion was removed after ostectomy of buccal cor...

BACKGROUND Bell´s palsy is the most common cause of facial paralysis worldwide and the most common disorder of the cranial nerves. It is a diagnosis of exclusion, accounting for 60-75% of all acquired peripheral facial nerve palsies. Our case shows the first case of a microcystic adnexal carcinoma-like squamous cell carcinoma as a cause of facial nerve palsy. CASE PRESENTATION The patient, a ...

Peripheral nerve injuries remain a challenge for reconstructive surgeons with many patients obtaining suboptimal results. Understanding the level of injury is imperative for successful repair. Current methods for distinguishing healthy from damaged nerve are time consuming and possess limited efficacy. Confocal laser endomicroscopy (CLE) is an emerging optical biopsy technology that enables dyn...

Investigators from Mayo Clinic in Rochester, MN, report the utility of nerve biopsy as a diagnostic tool in their institution.