A study of the transient potential signals obtained with a cation-selective electrode based on an ion-exchanger was carried out for solutions following individual cations at different concentrations: H+, Li+, Na+, K+, Rb+, Mg2+, Ca2+, choline (Ch+), acetylcholine (AcCh+), and procaine (Pr+). Three general types were distinguished depending value selectivity coefficient corresponding ion. princi...

X-ray powder diffraction (XRPD) analysis of intact multi-component consolidated mixtures has significant potential owing to the ability to non-destructively quantify and discriminate between solid phases in composite bodies with minimal sample preparation. There are, however, limitations to the quantitative power using traditional univariate methods on diffraction data containing features from ...

Purpose. The purpose of this study was to demonstrate the use of near-infrared (NIR) spectrometry for the in vitro quantification of econazole nitrate (EN) and estradiol (EST) in human skin. Methods. NIR spectra were collected from EN and EST powders to verify the presence of NIR chromophores. One percent EN cream, a saturated solution of EN, or 0.25% EST solution was applied to human skin. NIR...

J. Chemom A new procedure with high ability to enhance prediction of multivariate calibration models with a small number of interpretable variables is presented. The core of this methodology is to sort the variables from an informative vector, followed by a systematic investigation of PLS regression models with the aim of finding the most relevant set of variables by comparing the cross-validat...

We argue that programming high-end stream-processing applications requires a form of coordination language that enables the designer to represent interactions between stream-processing functions asynchronously. We further argue that the level of abstraction that current programming tools engender should be drastically increased and present a coordination language and component technology that i...

The use of a membrane-based continuous flow displacement immunoassay for detection of nanomolar quantities of explosives is demonstrated, and the kinetics of this system are characterized through experimentation. Antibodies of 2,4,6-trinitrotoluene (TNT) are immobilized onto a porous membrane with surface reactive sites designed to facilitate the covalent binding of the antibody. After saturati...

An analytical system for a one-step immunoassay has been constructed using the concept of immunochromatography. The system employed two different antibodies that bound distinct epitopes of an analyte molecule: an antibody labeled with a signal generator (e.g., colloidal gold), which was placed in the dry state at a predetermined site on a glass-fiber membrane, and another antibody immobilized o...

Electrochemical stripping analysis (anodic, cathodic, or adsorptive) is usually based on the pre-concentration of a target analyte working electrode surface and then measuring its quantity via direct quantitative electrochemical transformation (with refreshed afterwards). In this work, we demonstrate new approach to carry out non-adsorbing species, thus not being directly pre-concentrated (WE),...