There is a high incidence of hypoxic-ischaemic brain injury and intraventricular haemorrhage in newborn infants, particularly those born preterm. Many die during the newborn period or suffer permanent neurodevelopmental handicaps. Hypoxic brain injury develops over several hours and could potentially be influenced by intervention. At present, no drug exists that effectively prevents infant brai...

Abstract Transplacental transmission of Zika virus has been reported during all trimesters pregnancy and might lead to central nervous system anomalies, including microcephaly. We report 3 cases perinatal infection identified the epidemic in Colombia provide detailed descriptions clinical features, diagnosis, neurodevelopmental outcome at 18 months age (corrected).

OBJECTIVES The study objectives were to compare the neurodevelopmental outcomes of preschool survivors of the Fontan procedure with those of children with congenital heart disease undergoing biventricular repair and to investigate predictors of neurodevelopmental outcome for those with single ventricle congenital heart disease, including hypoplastic left heart syndrome. METHODS Neurodevelopme...

Background: Maternal parvovirus B19 infection can lead to serious consequences in the fetus including fetal death, non-immune hydrops fetalis and possibly long-term adverse neurodevelopmental outcome. To date, there has been no systematic review of the literature regarding long-term outcomes of these infants and children. Objective: To systematically review the literature on the long-term neuro...

BACKGROUND Preterm infants are at risk for neurodevelopmental sequelae even in absence of major cerebral lesions. The hypothesis that Human Recombinant Erythropoietin (rEpo) could improve the neurodevelopmental outcome in risk neonates has raised the highest interest in recent years. METHODS A group of preterm neonates born at a gestational age ≤ 30 weeks and free from major cerebral lesions ...

Objective: This study aims to determine the influence of high-risk factors and the effect of early intervention on abnormal neurodevelopmental outcomes in preterm infants with certain risk factors. Methods: The outcome of neurodevelopment was confirmed by Gesell scores. Associations between high-risk factors and neurodevelopmental outcome were examined by chi-square test and logistic-regression...

INTRODUCTION The Disability and Perinatal Care report published by the National Perinatal Epidemiology Unit and Oxford Regional Health Authority in 1994 emphasised that data on the neurodevelopmental outcomes of neonates requiring intensive care should be formally collected. Over the last 40 years, survival rates of high-risk infants have improved but these have not been matched with parallel i...