OBJECTIVE The authors report three cases of neuroleptic malignant syndrome (NMS) induced by atypical antipsychotics (olanzapine and clozapine) which showed classic features of NMS including muscular rigidity and prominent fever. METHOD Case reports. RESULTS A 66-year-old man with dementia and alcohol abuse developed NMS while on olanzapine for agitation and combativeness. A 62-year-old man ...

Delirium or acute confusional syndrome is a common problem in geriatric patients, although its diagnosis often overlooked, especially hypoactive form. Risk factors for delirium are previous cognitive alterations and certain comorbidities, different environmental organic typical of critically ill patients. associated with increased short- long-term mortality, to the prolongation mechanical venti...

Ischemic colitis is the most common subtype of intestinal ischemia usually resulting from vasospasm, vessel occlusion or mesenteric hypoperfusion. Neuroleptics have seldom been linked to ischemic colitis by blocking peripheral anticholinergic and antiserotonergic receptors inducing severe gastrointestinal paresis. We report a young patient with severe ischemic colitis requiring surgery due to n...

There is a growing medical and public concern about neuroleptic-induced persistent tardive dyskinesia. The clinician faces a difficult dilemma because there are no effective substitutes for neuroleptics in the treatment of a majority of schizophrenic patients. In dealing with this dilemma, the physician should 1) periodically assess indications for neuroleptics in each patient, 2) use the lowes...

Abstract Background Neuroleptic malignant syndrome (NMS) is an uncommon and lethal side effect of neuroleptics. The clinical expression this diverse. Even with criteria diagnosis, it hard to recognize easily. We report a series 25 cases NMS among patients hospitalized in psychiatric service at Oujda for 5 years. have described the characteristics these patients, treatments received, management,...

Although vascular chorea often comes into remission spontaneously, a few patients may remain with persistent movement disorder. Most movements respond well to neuroleptics as well as other antidopaminergic drugs, but some patients show poor responses to those neuroleptics. Topiramate is a widely used of broad-spectrum anticonvulsant possessing a complex mechanism of action. It has been proven t...

The results of long experience with psychotropic drugs in the treatment of chronic and severe pain resistant to ordinary therapy are reported. In 103 in-patients with chronic and severe pain caused by neurological conditions and treated with a combination of thymoleptics and neuroleptics, 82% showed a marked improvement. These encouraging results are compared with the results of other studies p...

Abstract Background The therapeutic decision toward patients with schizophrenia is very different from one psychiatrist to another when faced potentially similar clinical symptoms. It depends on many factors that are related the patient’s and doctor’s profiles, drug’s characteristics. To date, no study has been conducted in Morocco prescribing habits of psychiatrists schizophrenia. objectives o...

Examines the issues around conventional schizophrenia treatment including the problems with side effects and noncompliance, the introduction of newer atypical neuroleptics and their potential for improvement, and issues around pharmaceutical research and public pressures to get new medications approved. Also discusses costs and benefits of atypical neuroleptics in comparison with conventional n...