BACKGROUND Choroidal malignant melanoma is a rare intraocular cancer in Asian Indian population. There is a paucity of data from our population comparing iodine 125 (I-125) brachytherapy and enucleation. AIM This study aims to compare two groups of choroidal melanoma patients treated with either I-125 brachytherapy or enucleation in the Asian Indian population. OBJECTIVES To evaluate the lo...

Although surgery is usually the first-line treatment for nonmelanoma skin cancers, radiotherapy (RT) may be indicated in selected cases. Radiation therapy as primary therapy can result in excellent control rates, cosmetics, and quality of life. Brachytherapy is a radiation treatment modality that offers the most conformal option to patients. A new modality for skin brachytherapy is electronic b...

BACKGROUND To clarify the significant clinicopathological and postdosimetric parameters to predict PSA bounce in patients who underwent low-dose-rate brachytherapy (LDR-brachytherapy) for prostate cancer. METHODS We studied 200 consecutive patients who received LDR-brachytherapy between July 2004 and November 2008. Of them, 137 patients did not receive neoadjuvant or adjuvant androgen depriva...

Introduction: Environmental and occupational human exposure from neutron source can lead to the serious biologic effects. The aim of this study is to evaluate the cancer incidence risk for various human organs at different neutron dose levels due to exposure from an Americium-241/Beryllium (Am-241/Be), a standard neutron source for calibration purposes. Material and Methods: We measured ambient...

Neutron sources employed in different applications in both medicine and industry. Due to the harmful effects of neutron particles on living organisms, radiation shields have played a vital role in radiation protection against neutrons. In recent decade, numerous investigations conducted on the design and fabrication of nanocomposites as more efficient shielding materials against fast and therma...

background: a boron neutron capture therapy (bnct) facility, based on a dt neutron generator, with the final goal to find out a potential, alternative, solution to existing bnct treatment facilities which are based on nuclear reactors is examined. materials and methods: with the aim of the mcnp4b monte carlo code different beam-shaping assembly (bsa) configurations were considered. lead was sel...

in this research, cobalt and nickel sulfide nanoparticles (nps) were grown on almcm-41 matrix by using ion exchange method. the prepared samples were irradiated by thermalized neutron that emitted from am-be source up to fluencies (7.9+e9n/cm2). after that, x-ray diffraction (xrd), uv-vis spectroscopy, fourier transform infrared (ftir), scanning electron microscopy (sem) and transmission electr...

Cobalt-60 (Co-60) is a relatively new source for the application of high-dose rate (HDR) brachytherapy. Radiation dose to the rectum is often a limiting factor in achieving the full prescribed dose to the target during brachytherapy of cervical cancer. The aim of this study was to measure radiation doses to the rectum in-vivo during HDR Co-60 brachytherapy. A total of eleven HDR brachytherapy t...

Optimal treatment for patients with only local prostate cancer recurrence after external beam radiation therapy (EBRT) failure remains unclear. Possible curative treatments are radical prostatectomy, cryosurgery, and brachytherapy. Several single institution series proved that high-dose-rate brachytherapy (HDRBT) and pulsed-dose-rate brachytherapy (PDRBT) are reasonable options for this group o...

Planned in-situ radiosensitization may improve the therapeutic ratio of image guided I prostate brachytherapy. Spacers used in permanent implants may be manufactured from a radiosensitizer-releasing polymer to deliver protracted localized sensitization of the prostate. Such devices will have a limited drug-loading capacity, and the drug release schedule that optimizes outcome, under such a cons...