نتایج جستجو برای: neutrophil infiltration

تعداد نتایج: 90440  

Journal: :Molecules 2013
Yau-Hung Chen Wei-Hua Wang Yun-Hsin Wang Zi-Yu Lin Chi-Chung Wen Ching-Yuh Chern

The aim of this study was to investigate novel chalcones with potent anti-inflammatory activities in vivo. Chalcone and two chalcone analogues (compound 5 and 9) were evaluated using a caudal fin-wounded transgenic zebrafish line "Tg(mpx:gfp)" to visualize the effect of neutrophil recruitment dynamically. Results showed that treatment with compound 9 not only affected wound-induced neutrophil r...

Journal: :European Journal of Vascular and Endovascular Surgery 1998

2014
Caitlin Naylor Stacey Burgess Rajat Madan Erica Buonomo Khadija Razzaq Katherine Ralston William A. Petri

UNLABELLED Amebiasis is an enteric infection caused by Entamoeba histolytica, with symptoms ranging in severity from asymptomatic colonization to dysentery. Humans with the Q223R leptin receptor mutation have increased susceptibility to amebiasis, but the mechanism has been unclear. Using a mouse model expressing the mutation, we tested the impact of the Q223R mutation on the innate immune resp...

2018
Zhou Zhou Ming-Jiang Xu Yan Cai Wei Wang Joy X. Jiang Zoltan V. Varga Dechun Feng Pal Pacher George Kunos Natalie J. Torok Bin Gao

Background & Aims Hepatic infiltration of neutrophils is a hallmark of steatohepatitis; however, the role of neutrophils in the progression of steatohepatitis remains unknown. Methods A clinically relevant mouse model of steatohepatitis induced by high-fat diet (HFD) plus binge ethanol feeding was used. Liver fibrosis was examined. In vitro cell culture was used to analyze the interaction of ...

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