Abstract We explored the prognostic impact of simple indices that reflect immunological milieu (neutrophils to lymphocyte ratio [NLR] and systemic immune-inflammation [SII]) in 49 platinum-resistant relapsed ovarian cancer patients. The median progression-free survival (PFS) overall (OS) were 4 8 months, respectively. Patients with a lower NLR (?2.89) had better PFS (5 vs. 2 months [p = 0.02]) ...

We investigated whether elevated neutrophil-to-lymphocyte ratio ( NLR ) was associated with poor anti-tumor immunity and prognosis in patients with intrahepatic cholangiocarcinoma ( ICC ). Clinicopathologic data of 102 patients with ICC who underwent hepatectomy was retrospectively analyzed. The Kaplan-Meier method and Cox regression model were used to analyze the survival and prognosis. The pe...

Background: COVID-19 is a highly infectious disease that necessitates simple and rapid methods for recognising severe patients. Aims: To correlate between chest lesions in CT, neutrophil-lymphocyte ratio (NLR), platelets-lymphocytes patients with COVID-19, to detect their cut-off values as an early warning of Egyptian Subjects Methods: A cross-sectional study included 100 adult attending Ahmed ...

Comparison of isolated human neutrophils and lymphocytes in short-term tissue culture revealed marked differences in their rates of lipid biosynthesis. Ficoll-Hypaque gradients were used to separate lymphocytes and neutrophils from the blood of normal subjects. Neutrophils incorporated more palmitate into cell lipids (151.0 +/- 16.6 nmole/hr/10(8) cells) than lymphocytes (41.6 +/- 4.1). By cont...

BACKGROUND PD-L1 expression on neutrophils contributes to the impaired immune response in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC remains unclear. METHODS We investigated the phenotype and morphology of neutrophils infiltrated in tumour tissues from both patients with HCC and hepatoma-bearing mice. RESULTS We found that neutrophils dominantly infi...

Purpose More and more patients with community-acquired pneumonia have been detected Chlamydia psittaci ( C. ) infected using metagenomic next-generation sequencing (mNGS). Previously, this was unheard of, several presented severe even required ECMO. We aimed to clarify the clinical characteristics of find out if there are any possible predictors pneumonia. Methods In retrospective study, we inc...

INTRODUCTION Leukocytosis, predominantly neutrophilia, has previously been described following ST elevation myocardial infarction (STEMI). The exact contribution of this phenomenon to the clinical outcome of STEMI is yet to be shown. We examined cellular inflammatory response to STEMI in the blood and its association with in-hospital mortality and/or adverse clinical events. METHODS In this c...