Postmastectomy nipple necrosis is a factor that leads to poor aesthetic outcome in breast reconstruction because of the unique projective structure nipple. We present case successful using de-epithelialized rectangular flap. A 45-year-old woman was diagnosed with left cancer. She had vertical scar below nipple-areolar complex due previous reduction mammoplasty. underwent nipple-sparing mastecto...

The present experiment investigated the relationship between motor activity and oral grasping of an artificial nipple in newborn rats. Pups orally grasped the artificial nipple, and they performed more and longer oral grasps in the latter portion of the nipple presentation. Motor activity was cyclical, and this cyclicity was evident before and during presentation of the artificial nipple. The o...

NHNA: nevoid hyperkeratosis of the nipple and/or areola INTRODUCTION Nevoid hyperkeratosis of the nipple and/or areola (NHNA) is an uncommon skin disease without welldefined etiology, reported for the first time in 1923. The disease is characterized by slowly growing verrucous thickening and brown pigmentation of the areola or nipple. Here we report a lesion on the nipple clinically and dermosc...

The chromatin remodeler ISWI is capable of repositioning clusters of nucleosomes to create well-ordered arrays or moving single nucleosomes from the center of DNA fragments toward the ends without disrupting their integrity. Using standard electrophoresis assays, we have monitored the ISWI-catalyzed repositioning of different nucleosome samples each containing a different length of DNA symmetri...

BACKGROUND The use of nipple-sparing mastectomy (NSM) for both breast cancer treatment and risk reduction is increasing. There is no randomized data comparing nipple-sparing mastectomy with standard mastectomy techniques. There is evidence to suggest that ductal and lobular breast cancer arises in the terminal duct/lobular unit (TDLU). This study was undertaken to determine whether TDLUs exist ...

BACKGROUND Nipple pain and damage in breastfeeding mothers are common causes of premature breastfeeding cessation. Peppermint water is popularly used for the prevention of nipple cracks in the North West of Iran. The aim of this study was to determine the effectiveness of peppermint water in the prevention of nipple cracks during breastfeeding in comparison with the application of expressed bre...

BACKGROUND Numerous techniques have been used to achieve long-term projection of the nipple following nipple-areola reconstruction. However, the reconstructed nipple loses projection over time. We describe a technique that uses local flaps to improve the lost projection of reconstructed nipples. METHODS Between November 2013 and March 2015, nine patients (11 nipples) underwent revisional nipp...

Nipple reconstruction is a commonly performed component of breast reconstruction. A nipple reconstructed using local skin flaps requires protection from trauma. Here we describe a novel, effective, simple, rapid, inexpensive, and convenient method to protect a reconstructed nipple in the early postoperative period.