Nitrofurans (furazolidone, furaltadone, nitrofurantoin, nitrofurazone) belong to a wide range of synthetic antibiotics used in the prevention gastrointestinal infections livestock, aquaculture and beekeeping. They were also as food supplements stimulate growth. In 1995, use nitrofurans veterinary medicine was banned European Union because carcinogenic potentially harmful effects humans. Illegal...

background split- thickness skin graft is one of the most common operations in plastic surgery. it is always painful and patient discomfort from donor site often is more significant than recipient site. there is not still a standard method for treatment of the donor site. the purpose of this study was to determine the best method of dressing the donor site among three different methods with res...

DinB (DNA Pol IV) is a translesion (TLS) DNA polymerase, which inserts a nucleotide opposite an otherwise replication-stalling N(2)-dG lesion in vitro, and confers resistance to nitrofurazone (NFZ), a compound that forms these lesions in vivo. DinB is also known to be part of the cellular response to alkylation DNA damage. Yet it is not known if DinB active site residues, in addition to aminoac...

In the title compound, C(18)H(18)ClN(5)O(3), the hydrazinecarboxamide N-N-C(O)-N unit is nearly planar [maximum deviation = 0.074 (2) Å] and is inclined at a dihedral angle of 57.43 (7)° with respect to the plane of the attached benzene ring. The chloro-phenyl group makes dihedral angles of 19.71 (7) and 34.07 (6)° with the pyrazole and benzene rings, respectively. In the crystal, pairs of N-H⋯...

This study investigated the influence of pulsed low-level laser therapy (LLLT) on the healing of a third-degree burn in a rat model. Two third-degree burns (distal and proximal) were made in the skin of 74 rats. Rats were divided into four groups. In group 1, the distal burn received LLLT with laser switched off; in groups 2 and 3, distal burns were treated with a 3,000 Hz-pulsed infrared diode...

Previously it has been shown that Furacin (5-nitro-2-furaldehyde semicarbazone) inhibited the dismutation of pyruvate by whole resting cells of Micrococcus pyogenes var. aureus (1). Other earlier studies have also shown that both pyruvate dismutation and the formation of acetylmethylcarbinol (AMC) by cell-free extracts of pigeon breast muscle were markedly inhibited by Furacin (2). We are repor...