the tumors in which odontogenic differentiation is fully expressed are the odontomas. odontomas are considered as hamartomas rather than a true neoplasm. these tumors are composed of enamel, dentine, cementum and pulp tissue. it is most commonly associated with the eruption of the teeth. they are usually discovered on routine radiographic examination. in exceptional cases, the odontoma erupts i...

UNLABELLED Aristolochia manshuriensis has been used for centuries in Chinese medicinal system for their versatile medicinal uses. Recent studies have revealed two new aristolactames (compound A and B) with γ-lactame ring fused with the phenentherene ring as potent inhibitors of human Cycline Dependent Kinase2 (CDK2). Studies on aristolactames and related compounds claim for their CDK2 inhibitio...

This work proposes a new method for Co(II) determination based on the use of the triblock copolymer as micellar medium instead of chloroform. The proposed strategy is environmental friendly because the copolymer is biodegradable and nontoxic. The method is based on the formation of a cobalt-1-nitroso-2-naphthol complex, in the micellar triblock copolymer compound solution constituted by polyeth...

Concern over polycyclic aromatic hydrocarbons (PAHs) in foodstuffs was started during the 1960s and 1970s, where two classes of food toxicants producing tumours have been focused i.e. polycyclic aromatic hydrocarbons (PAHs) and N-nitroso compounds (Jägerstad and Skog, 2005). PAHs are referring to a series of organic compound containing two or more fused aromatic rings (Danyi et al., 2009; El-Ba...

Tyramine is a biogenic compound derived from the decarboxylation of the amino acid tyrosine, and is therefore present at important concentrations in a broad range of raw and fermented foods. Owing to its chemical properties, tyramine can react with nitrite, a common food additive, in the acidic medium of stomach to form N- and C-nitroso compounds. Since toxicology studies have shown that the pr...

Twelve vicinally substituted nitro-nitroso compounds (pseudonitrosites) were synthesized, nine of them for the first time. In the solid state the dimeric azodioxides are present. In the class of the pseudonitrosites 2a-h, all compounds exhibited comparatively strong antiplatelet activity in vitro (Born test, collagen). Four of them showed an IC50 below 10 microM, 2a being the most active substa...

The newly developed DNA-biosensor is a very promising tool for the investigation and study of the action of drugs specifically designed to interact with DNA. In this work the electrochemical reduction of nitroimidazole drugs was studied in the presence of DNA immobilized onto the surface of a glassy carbon electrode. This enabled preconcentration of the drug onto the electrode surface, which wa...

Brain tumors are the second most common cancer in children after leukemia, yet the etiology of childhood brain tumors remains unknown. Tobacco smoke contains several dozen compounds that are known to be carcinogens. Among these are N-nitroso compound precursors, principally tobacco-specific nitrosamines. Although smoking has not been identified as a significant risk factor for the development o...

In the centrosymmetric title compound, [Ni(C7H6FN2O2)2(H2O)2], the Ni(II) cation is in a slightly distorted octa-hedral environment and is surrounded by four O atoms from the N-O groups of the organic ligands [Ni-O = 2.0179 (13) and 2.0283 (12) Å], and two water mol-ecules [Ni-O = 2.0967 (14) Å]. The N-(2-fluoro-benz-yl)-N-nitroso-hydroxy-laminate monoanions act as bidentate chelating ligands. ...