Pyramidal neurons in the piriform cortex from olfactory-discrimination-trained rats have reduced postburst afterhyperpolarization (AHP), for 3 days after learning, and are thus more excitable during this period. Such AHP reduction is caused by decreased conductance of one or more of the calcium-dependent potassium currents, I(AHP) and sI(AHP), that mediate the medium and slow AHPs. In this stud...

Cognitive control refers to the ability to repress our instantaneous urges in favor of more appropriate responses. Current debate concerns whether cognitive control effects that are studied in the laboratory (e.g. Stroop tasks) actually reflect the operation of a cognitive control system (adaptation theory) or instead merely reflect side effects of feature binding processes (binding theory). Th...

The ultrastructure of the adrenal medulla in adult laboratory animals has been described in a number of reports (Lever, 1955; Sjostrand & Wetzstein, 1956; Wetzstein, 1957; de Robertis & vaz Ferreira, 1957; Eranko & Hanninen, 1960; Yates, 1963,1964a, b, c; Coupland, 1965 a, b; Elfvin, 1965 a, b). Since the introduction of the glutaraldehyde fixation technique, it has been possible to distinguish...

Hepatocytes respond with repetitive cytosolic calcium spikes to stimulation by vasopressin and noradrenalin. In the intact liver, calcium oscillations occur in a synchronized fashion as periodic waves across whole liver lobules, but the mechanism of intercellular coupling remains unclear. Recently, it has been shown that individual hepatocytes can have very different intrinsic oscillation frequ...

Serotonin ve/veya noradrenalin üzerinden etki yapan geleneksel antidepresanlar depresif hastaların yaklasık yarısında etkisiz kalmakta ve etkin olmaları durumunda da etkilerinin başlaması geç olmaktadır. Glutamaterjik sistemin majör depresif bozukluğun nöropatolojisinde ve tedavisinde önemli rol oynadığına dair kanıtlar giderek artmaktadır. Yakın zamanda ketaminin tek doz uygulanmasıyla hızlı v...

To investigate the relationships between gastric change accompanying patients with acute stroke and the function of the autonomic nervous system and pituitary-adrenal system, studies on the gastroendoscopic technique and biochemical observations were done in 122 patients. The mean urinary noradrenalin and adrenalin excretions were elevated in patients with acute gastric changes, especially in p...