نتایج جستجو برای: ns3

تعداد نتایج: 2731  

Journal: :F1000Research 2021

Background: Exposure to 2.5-micron diameter air pollutants (PM2.5) has been associated with an increased risk of illness and death worldwide; however, in Latin American health impacts assessment this factor is scarce. Medellín one the most polluted cities region, a population growth rate that twice as high other Colombian cities, which implies grow...

Journal: :F1000Research 2022

Background: The key to successful outcomes in time-sensitive emergencies involves a pivotal role played by bystanders identifying and initiating first response. This turn depends on their awareness perspective regarding the same. Objective: study aimed assess existing attitude response students pursuing graduati...

Journal: :F1000Research 2022

Background: Actual and potential drug–drug interactions of psychotropic drugs in patients the COVID-19 Medicine Service Villa El Salvador Emergency Hospital during months February to July, 2021. Methods: The study is deductive, retroprospective, quantitative, applied, cross-sectional observational. instrument used was a collection ...

Journal: :F1000Research 2022

Background: Parkinson's disease is an attractive model to extend research towards a better understanding of the interrelationship between genes and environment (exposome) therefore ideal for polypharmacological approach due its clinical heterogeneity. Methods: In this paper, we present series chemical scaffolds extracted from ChEMB...

Journal: :vaccine research 0
mh pouriayevali department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran . t bamdad department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran . sm sadat department of hepatitis and aids, pasteur institute of iran. tehran, iran. f sabahi department of virology, faculty of medical sciences, tarbiat modares university, tehran, iran . mr aghasadeghi department of hepatitis and aids, pasteur institute of iran. tehran, iran. sh yazdani department of virology, school of public health, tehran university of medical sciences, tehran, iran.

introduction: hepatitis c virus (hcv) is one of the major medical problems. human and chimpanzees are the only specific hosts which are naturally susceptible to hcv infection. mice and other common laboratory animals are resistant to the virus, hence hcv prophylactic and therapeutic researches are very difficult and challenging. hcv non-structural protein 3 (ns3) is one of the most attractive t...

Journal: :F1000Research 2021

Background: Proper feed formulation is required for successful fish farming activities. Therefore, it necessary to provide optimal growth so that the cultivation business generates profits. Currently, there very limited information about appropriate Caranx ignobilis, causing problems with its development. This study aims different protein lev...

Journal: :F1000Research 2022

Background: Biochemical and biophysical factors jointly regulate the cellular dynamics in many physiological processes. It is therefore imperative to include multiplexed microenvironment cues when employing in vitro cell-based assays model processes. Methods: To meet this need, we have developed a modular p...

Journal: :F1000Research 2023

Introduction: This report describes the use of conjunctival flaps to enable survival type I keratoprosthesis (KPro) in two cases bilateral severe total limbal stem cell deficiency (LSCD) following chemical burns. Presentation case: Two patients had a history injury with lime. On examination, presenting...

Journal: :Wellcome Open Research 2021

Background: Adequate staffing is key to the delivery of nursing care and thus improved inpatient health service outcomes. Several systematic reviews have addressed relationship between nurse these Most primary studies within each review are likely be from high-income countries which different practice contexts low middle-income (LMICs), although this has not been for...

Journal: :Nucleic acids research 2001
A J Tackett L Wei C E Cameron K D Raney

Hepatitis C virus (HCV) helicase, non-structural protein 3 (NS3), is proposed to aid in HCV genome replication and is considered a target for inhibition of HCV. In order to investigate the substrate requirements for nucleic acid unwinding by NS3, substrates were prepared by annealing a 30mer oligonucleotide to a 15mer. The resulting 15 bp duplex contained a single-stranded DNA overhang of 15 nt...

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