Cloning of mammals by nuclear transfer (NT) results in gestational or neonatal failure with at most a few percent of manipulated embryos resulting in live births. Many of those that survive to term succumb to a variety of abnormalities that are likely due to inappropriate epigenetic reprogramming. Cloned embryos derived from donors, such as embryonic stem cells, that may require little or no re...

The toxicity and genotoxicity of wastewater from eight gasoline stations in Brasília, Brazil's capital city, was studied by assessing chromosomal aberrations, chromosomal malsegregation and the mitotic index in Alliumcepa root cells, and the occurrence of micronucleus and nuclear abnormalities in peripheral erythrocytes of tilapia fish (Oreochromis niloticus). The content of gasoline station ef...

Despite excellent immediate clinical results and anatomic improvement of critical coronary artery stenosis, functional abnormalities have been noted to persist for several days or weeks after successful percutaneous transluminal coronary artery balloon angioplasty (PTCA) (1–13). Even without eventual angiographic restenosis, persistent abnormalities of wall motion (1,2), myocardial perfusion (3...

Aim: Evaluation of nuclear anomalies in exfoliated buccal epithelial cells of petrol station attendants and oral squamous cell carcinoma patients. Materials and methods: Study was carried out on 60 subjects. 20 petrol pump attendants, 20-squamous cell carcinoma patients and 20 healthy subjects. They were asked questions regarding their life style and personal factors (age, duration of working i...

iniencephaly is a rare kind of neural tube defect that is classified into two types of iniencephaly apertus and iniencephaly clausus. this anomaly could be diagnosed prenatally by obstetric ultrasonography and terminated by therapeutic abortion; however, it could be undiagnosed until birth similar to our case due to the abnormal position of the fetus or lack of experience of the sonographer. du...

nuchal translucency (nt) measurements in the first trimester screening between 11 and 14 weeks’ gestation are regarded as a clear marker for aneuploidies. the presence of a thickened nt, even if the karyotype is normal, can be associated with structural abnormalities. having an abnormal screening of nt, parents and physicians could face dilemma over abortion particularly in a case of ivf/icsi f...

extended abstract introduction zanjan has recently enjoyed considerable population and physical growth. the rapid irregular growth in population number caused unfavorable formation of informal settlement areas in the city. islamabad is of the largest informal accommodation regions in zanjan which was built as a consequence of massive rural migration during 1970s. although the area, at present,...

Patients with progeroid syndromes such as mandibuloacral dysplasia, type B (MADB) and restrictive dermopathy (RD) harbor mutations in zinc metalloproteinase (ZMPSTE24), an enzyme essential for posttranslational proteolysis of prelamin A to form mature lamin A. Dermal fibroblasts from these patients show increased nuclear dysmorphology and reduced proliferation; however, the efficacy of various ...

AIMS The aim of this study was to find out the characteristic morphology of malignant atypical cells which were missed on routine cytology of urine. MATERIALS AND METHODS In this retrospective study, we examined detailed cytomorphology of 18 cases of atypical urinary cytology which were missed on routine examination and were further proved on histopathology as transitional cell carcinoma (TCC...