Accepted for publication June 22, 2012. Study received institutional review board approval. * Correspondence: Androfert, Andrology and Human Reproduction Clinic, Center for Male Reproduction, Av. Dr. Heitor Penteado, 1464, Campinas, São Paulo 13075-460, Brazil (telephone: 55 19 3295-8877; FAX: 55 19 3294-6992; e-mail: [email protected]). Purpose: We evaluated the retrieval rates and re...

Background The genetic association between cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations and male infertility due to congenital bilateral absence of vas deferens (CBAVD) is well established. Mutant CFTR, however may also be involved in the etiology of male infertility in non-CBAVD cases. The present study was conducted to estimate the frequency of ΔI507 and ΔF508 CFT...

Objective: To evaluate the outcome of repeated TESE/ICSI, in patients with non-obstructive azoospermia, to collect sufficient information for adequate counseling of the patients. Design: Retrospective study Setting: The Egyptian IVF-ET center Materials and Methods: 41 patients suffering from non-obstructive azoospermia underwent 59 repeated TESE/ICSI cycles. All of the patients had repeated TES...

background: deletions of the daz (deleted in azoospermia) genes within the human y chromosome's azfc region are the most common cause of spermatogenesis failure. these deletions are usually assessed by analyses of genomic dna ex­tracted from peripheral leukocytes. daz genes are expressed in male germ cells. in this prospective study, we investigated daz expression and deletion in 102 consecutiv...

STUDY QUESTION How do live birth rates compare after intracytoplasmic sperm injection (ICSI) for men with obstructive azoospermia when using sperm derived from testicular sperm extraction (TESE) versus microsurgical epididymal sperm aspiration (MESA)? SUMMARY ANSWER Our study suggests that proximal epididymal sperm (from MESA) result in higher live birth rates as compared with testicular sper...