Hematogenous pyelonephritis was produced in rats utilizing multiple strains of Escherichia coli, a strain of Klebsiella pneumoniae, and a strain of Proteus mirabilis. Three patterns of hematogenous pyelonephritis occurred which represent an interrelationship between an immune response to the infecting bacteria and the development of obstructive uropathy as a consequence of infection. First, the...

Fetal intervention for obstructive uropathy was first performed at the University of California, San Francisco in 1981 [1]. Since then diagnostic criteria for fetal intervention have been laid down to assist in proper patient selection [1-3]. Unilateral fetal hydronephrosis doesn’t require prenatal intervention; but prenatal intervention might be required in selected cases, especially when hydr...

A 22-year-old male with obstructive uropathy and renal failure was given pre-operative haemodialysis. He collapsed five hours later. Autopsy revealed massive intrarenal haemorrhage and rupture of a dilated superior calyx intraperitoneally. Anticoagulation employed during haemodialysis was probably responsible for this spontaneous renal haemorrhage and subsequent calyceal rupture.

Bladder involvement in inguinal hernia is relatively rare, 1-4%, although the incidence is increased to 10% with advancing age or obesity. There are several previously reported cases presenting with obstructive uropathy and renal failure, but all reversed with urinary diversion and hernia repair. We believe this to be the first reported case of bladder hernia leading to dialysis dependent chron...

Renal involvement as the first manifestation of sarcoidosis is rare and has never been reported in India. This report describes a 35 year old man who was admitted to the emergency department with a clinical diagnosis of acute on chronic renal failure, secondary to obstructive uropathy. Postmortem examination unexpectedly revealed disseminated sarcoidosis.

We report two cases of pan-proctocolectomy for ulcerative colitis who some time postoperatively developed an obstructive uropathy with the clinical and radiological features of retroperitoneal fibrosis. The incidence of this complication appears to be around 10% and the possibility of such a diagnosis should be borne in mind in any patient who has non-specific symptoms after surgery for ulcerat...

Anterior urethral valves are rare anomalies which cause obstructive uropathy in the lower urinary tract of young men. We discuss our illustrative case and review the English medical literature in order to analyze the clinicopathologic spectrum. We propose a hypothesis of embryology of this lesion and present guidelines for its management.

Background: Where in the infection occur repeatedly leaving residual inflammatory changes. It is more common in the presence of structural or functional anomalies of the urinary tract, which interfere with drainage of urine. Common organisms are E. coli in early infancy, while the later resistant organism like proteus and klebsiella predominate. Objective: To study, obstructive uropathy among c...

A 55 year old man presented with acute renal failure. He was grossly overweight with a BMI of 48 and had a past history of sleep apnoea, chronic lymphoedema and left ventricular dysfunction. Physical examination revealed a pendulous abdomen which extended to his knees and bilateral, irreducible inguinoscrotal hernias. Blood samples on admission revealed a serum creatinine of 187umol/l and an eG...

To cite: Kumar S, Lata S, Patidar Y. Thorax Published Online First: [please include Day Month Year] doi:10.1136/thoraxjnl-2013203954 Pleuropericardial effusion as a presenting feature raises the possibility of infectious, neoplastic and connective tissue disorders. However, unusual pathophysiological mechanisms may sometimes pose a diagnostic conundrum in certain clinical contexts. Simultaneous...