The present study was aimed to study the acute and subacute toxicity studies with orally administered 50% ethanolic leaves extract of Ocimum sanctum Linn (OSE). In acute toxicity tests, four groups of mice (n = 6/group/sex) were orally treated with doses of 200, 600, and 2000 mg/kg, and general behavior, adverse effects, and mortality were recorded for up to 14 days. In subacute toxicity study,...

Ethanol extracts of Ocimum sanctum Linn. and Tinospora cordifolia (Willd.) Miers ex Hook. f. & Thoms. were included for the present in vitro study. Pepsin was used as a substitute for HIV-protease to evaluate inhibitory activity of these extracts, as pepsin has close resemblance with HIV-protease in proteolytic activity. Extracts of O. sanctum and T. cordifolia showed potent inhibitory activity...

background: recent studies have shown that benzene extract of ocimum sanctum (o. sanctum) leaves induces the ultrastructural changes in the epithelial cells of the cauda epididymis, its subsequent recovery in the seminiferous epithelium and fertility of male albino rats. objective: our aim was to investigate the effect of benzene extract of o.sanctum leaves on the cauda epididymal sperm paramet...

The objective of the study was to investigate the anti-oxidant and anti-inflammatory effect of aqueous extract of Ocimum sanctum leaf. The antioxidant and anti-inflammatory activities were evaluated using in vitro Ferric reducing power, Free radical scavenging activity by DPPH method, hydroxyl radical scavenging activity, Nitric oxide radical scavenging activity, Hyaluronidase inhibition assay....