Calcium phosphate is attracting attention as a bone repair material and controlled-release carrier of various drugs such disease therapeutic agents anticancer agents. Compared with some bioabsorbable polymers, calcium phosphates have the advantage preventing pH decrease in surrounding body fluid. However, there are few studies comparing effect supporting substances different physicochemical pro...

The present author and coworkers have engaged in the research developments of inorganic phosphate materials with high performance, utilizing characteristic properties phosphates forms crystals glasses. review described our previous regarding (i) preparation fibrous octacalcium (Ca8H2(PO4)6∙5H2O) hydroxyapatite (Ca10(PO4)6(OH)2; HAp) particles due to anisotropic crystal growth, (ii) superplastic...

A novel, one-pot technique of synthesizing calcium phosphate whiskers was developed. Commercially available b-tricalcium phosphate (b-Ca3(PO4)2) powders were aged in unstirred 30% H2O2 solutions at 901C for 48 h in ordinary glass media bottles. Resultant samples consisted of whiskers (200 nm wide and 5 lmlong) of a biphasic mixture of octacalcium phosphate (OCP: Ca8H2(PO4)6 . 5H2O) and carbonat...

Introduction Intra-articular basic calcium phosphate (BCP) (hydroxyapatite, octacalcium phosphate, tricalcium phosphate) crystal-deposition disease is associated clinically with severe degenerative arthritis characterized by hyperplasia of the synovial lining and loss of intrasynovial collagenous structures [1]. The interaction of the crystals with inflammatory cells is believed to be a key fac...