نتایج جستجو برای: octreotate

تعداد نتایج: 223  

2011
Ann Erlandsson Eva Forssell-Aronsson Tomas Seidal Peter Bernhardt

BACKGROUND Small-cell lung carcinoma (SCLC) is an aggressive malignancy characterised by an early relapse, a tendency towards drug resistance, and a high incidence of metastasis. SCLC cells are of neuroendocrine origin and express high levels of somatostatin receptors; therefore, future treatment might involve targeting tumours with radiolabelled somatostatin analogues. This therapy induces abu...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Margret Schottelius Thorsten Poethko Michael Herz Jean-Claude Reubi Horst Kessler Markus Schwaiger Hans-Jürgen Wester

PURPOSE Despite excellent radionuclide characteristics, no (18)F-labeled peptides are available for quantitative peptide receptor mapping using positron emission tomography (PET) so far, mainly due to time-consuming multistep radiosyntheses with limited overall yields. A newly developed two-step chemoselective conjugation method allows rapid and high-yield [(18)F]fluorination of peptides via ox...

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