BackgroundUveitis is a vision-threatening inflammation and considered an ophthalmic emergency. It generally arises as result of autoimmune conditions, infections, or ocular trauma, but it may also occur isolated disorder. Over the past decades, several cases vaccine-associated uveitis have been described, with hepatitis B virus vaccine being leading cause.Clinical caseA case anterior in 23-year...

BACKGROUND Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes (POEMS) syndrome is an uncommon condition related to a paraneoplastic syndrome secondary to an underlying plasma cell disorder. Among the myriad of manifestations of the disease, ocular signs and symptoms are relatively prevalent, affecting about half of all patients with the disease. OBJECTIVE To...

Behçet's disease is a chronic systemic disorder characterized by recurrent uveitis, aphthous lesions of the mouth, and ulcerations of the genitalia. Vision loss from ocular involvement is frequently the presenting symptom and optometrists should be aware of the various ocular signs of Behçet's disease. Management of the Behçet's patient involves systemic therapy and therefore requires comanagem...

RATIONALE Axenfeld-Rieger syndrome (ARS) is a rare autosomal dominant disorder with ocular anterior segment dysgenesis and systemic anomalies. PATIENT CONCERNS A 28-year-old Chinese Han female was referred to Beijing Tongren Eye Center for progressive decrease of the visual acuity on her right eye in the past month. DIAGNOSES The patient was diagnosed as ARS with retinal detachment based on...

Rosacea is a common facial disorder characterized by centrofacial erythema, flushing, telangiectasia, edema, papules, pustules, ocular lesions, and rhinophyma in various combinations. The skin lesions most commonly affect the convex areas of the nose, cheeks, chin, and forehead. Rosacea is classified as erythematotelangiectatic (ETR), papulopustular, and phymatous subtypes, and as ocular and gr...

Aim: This study aimed at determining the prevalence and pattern of ophthalmic disorders among students of School for the Deaf, Akure, Ondo State, Nigeria. Methodology: This is a cross sectional descriptive study was conducted in October, 2011 as part of activities marking the Annual Physicians’ week of Nigerian Medical Association (NMA), Ondo State. Ethical clearance was obtained from the Ethic...

The serial application of electromyographic (EMG) and sensorimotor (SMR) biofeedback training was attempted with a 10-year-old boy presenting a triad of symptoms: an attention deficit disorder with hyperactivity, developmental reading disorder, and ocular instability. Symptom elimination was achieved, for all three aspects of the triad, following the procedure of first conditioning a decrease i...

Case report: Congenital disfiguring malformations are rare and usually have a multifactorial aetiology. Here we report on the ocular manifestations seen in a patient with Proteus syndrome. The retina showed retinal dysgenesia, retinal pigmentary abnormalities and optic nerve hypoplasia. Other abnormalities included strabismus and high myopia. Discussion: Proteus syndrome is a complex hamartomat...

Congenic mice of the MRL/Mp strain spontaneously develop an autoimmune connective tissue disease that shares immunologic and histopathologic features with the human disorders systemic lupus erythematosus, rheumatoid arthritis, and systemic vasculitis. The autoimmune disorder in these mice is markedly accelerated by the recessive gene lpr. Older MRL/Mp-lpr/lpr mice develop significant inflammato...