Title: CIRCULATING BIOMARKERS OF NITROOXIDATIVE STRESS IN YOUNG AND OLDER ACTIVE AND INACTIVE MEN Lori Beth Bjork, M.A., 2010 Directed By: Professor James M. Hagberg, PhD Department of Kinesiology Oxidative stress markers may be novel factors contributing to cardiovascular (CVD) risk. The purpose of this study was to examine the effects of long-term exercise, age, and their interaction on the p...

Increased stride-to-stride variability during walking characterizes gait instability and predicts falling in older adults. Walking while performing cognitive tasks (dual task walking) is also associated with increased risk of falling. The purpose of the study was to examine whether gait velocity and stride-to-stride variability in gait velocity differ in older adults compared with middle-aged a...

BACKGROUND Our purpose was to determine if aging had an influence on muscle blood flow independent of habitual physical activity levels. METHODS Blood flow was measured in the femoral artery by Doppler ultrasound after cuff occlusion of 10 minutes. Active and inactive older subjects (73 +/- 7 years) were compared to active and inactive young subjects (26 +/- 6 years). RESULTS Peak blood flo...

OBJECTIVES To explore differences in cerebral oxygen reserves during sleep in old and young adults. DESIGN Descriptive cross-sectional study. SETTING General clinical research center. PARTICIPANTS Nine old (aged 65-84) and 10 young (aged 21-39) adults. MEASUREMENTS Subjects were monitored during the first nightly sleep cycle using standard polysomnography, including measures of arterial...

Temporal dynamics of attention during postural perturbations in young and older adults were investigated. Nineteen young and older subjects performed simple reaction time tasks during translational platform perturbations. Auditory or visual stimuli were presented randomly at delays from the onset of the platform perturbation. Reaction time was slowed before and during the platform movement, par...

A 10-day cumulative irritation test was conducted to evaluate whether or not test subjects 65 years of age and older would rank eleven test materials the same as subjects 18 to 45 years of age The test materials consisted of mild to moderately irritating chemicals. The test articles were ranked similarly for both groups of subjects. Statistical analysis indicated no significant difference betwe...