the ip3r calcium release channel has been simulated using a stochastic simulation algorithm (ssa;gillespie algorithm) and de young-keiser model. a set of different concentration for cat' and ip3 havebeen used. considering the number of molecules in each state, a non linear behavior of the system can beseen clearly. the inhibiting role of the ca+2 on the open state (x110) has been studied. the d...

The simplest water diversion method in irrigation systems is using intakes. Measuring the mean velocity is one of the essential hydraulic parameters in increasing the efficiency of the intake. In this study, the mean velocity was predicted for different width ratios of an intake using ANN-MLP neural network model. In order to do that, the flow field within a 90-degree intake was first simulated...

Estimates of denitrification based on standard methods often cannot easily be extrapolated to entire ecosystems because of high spatial heterogeneity in rates of denitrification. Diel changes in the concentration of dinitrogen (N2) in running waters provide the basis for estimating denitrification by an open-channel technique in much the same way that ecosystem metabolism can be estimated from ...

Open channel block is a process in which ions bound to the inside of a channel pore block the flow of ions through that channel. Repulsion of the blocking ions by depolarization is a known mechanism of open channel block removal. For the NMDA channel, this mechanism is necessary for channel activation and is involved in neuronal plasticity. Several types of transient receptor potential (TRP) ch...

Recent studies of the bacterial mechanosensitive channel MscL have combined a number of different approaches to come up with a model for the channel gating mechanism.