Optic disc (OD) and fovea locations are two important anatomical landmarks in automated analysis of retinal disease in color fundus photographs. This paper presents a new, fast, fully automatic optic disc and fovea localization algorithm developed for diabetic retinopathy (DR) screening. The optic disc localization methodology comprises of two steps. First, the OD location is identified using t...

PURPOSE To investigate optic disc perfusion differences in normal, primary open-angle glaucoma (POAG), and normal tension glaucoma (NTG) eyes using optical microangiography (OMAG) based optical coherence tomography (OCT) angiography technique. DESIGN Cross-sectional, observational study. SUBJECTS Twenty-eight normal, 30 POAG, and 31 NTG subjects. METHODS One eye from each subject was scan...

PURPOSE To examine the roles of genetic and environmental factors in the optic disc in a classic twin study. METHODS Five hundred six pairs of twins were recruited to participate from the Twins U.K. Adult Twin Registry at St. Thomas' Hospital, London. Photographs of the optic disc were obtained, and the covariance of optic disc, cup, and rim areas within monozygotic (MZ) and dizygotic (DZ) pa...

The purpose of this study was to evaluate the relationship between central corneal thickness (CCT) and optic disc morphology in normal tension glaucoma (NTG). Patients with NTG underwent eye examination, optic disc imaging with Heildelberg Retina Tomograph II (HRT II) and ultrasound corneal pachymetry. The morphological parameters of the optic discs were used to classify the eyes into four grou...

This study was to analyse the degeneration of the Retinal Nerve Fiber Layer (RNFL) and optic disc and the relationship between optic nerve damage and the severity of cognitive impairment in patients with Alzheimer’s disease (AD) and Mild Cognitive Impairment (MCI). The RNFL thickness and optic disc variables were assessed by optical coherence tomography in patients with MCI and AD and control s...

PURPOSE To measure the optic disc rotation around the vertical and horizontal disc axis and to evaluate associations with general and ocular parameters. DESIGN Population-based study. METHODS In the Beijing Eye Study, 3468 participants (mean age:64.6±9.8 years; range:50-93 years) underwent an ophthalmological examination which included spectral-domain optical coherence tomography (OCT) with...

PURPOSE To examine the influence of body height, body weight, and body mass index (BMI) on optic disc parameters in a population-based study. METHODS The Singapore Malay Eye Study examined 3280 persons of Malay ethnicity, aged 40 to 80 years, of whom 2329 (71.0%) had reliable retinal scanning confocal laser tomography images for analyses. Intraocular pressure (IOP) was ascertained by Goldmann...

PURPOSE To determine the frequency of optic disc hemorrhages in a rural Indian population. METHODS The population-based Central Indian Eye and Medical Study included 4711 subjects. Mean age was 48.5±12.9 years (range: 30-100 years). Color optic disc photographs were examined. RESULTS Optic disc photographs were available for 4570 (97.0%) subjects. Prevalence of disc hemorrhages was 17/8869 ...

BACKGROUND Optic disc drusen, which are calcified deposits that form anterior to the lamina cribrosa in the optic nerve, may mimic papilledema. CASE REPORT We report herein three cases referred to us with suspicion of disc swelling and papilledema. Following ophthalmologic evaluation with B-scan ultrasound, red-free fundus photography, and computed tomography, the diagnosis of papilledema was...

purpose: to present a case of herpes zoster ophthalmicus (hzo) with consequent posterior ischemic optic neuropathy (pion). case report: a 58-year-old woman with a history of hzo in her right eye which was under treatment presented with loss of vision to no light perception. on examination, positive relative afferent pupillary defect was detected; however the optic disc was normal on ophthalmosc...