OBJECTIVE To determine whether texturing the optic edge of the intraocular lens reduces photic symptoms in patients with square-edged acrylic intraocular lense implants. METHODS Sixty patients underwent routine phacoemulsification performed by a single surgeon and were prospectively randomized to receive either the standard AcrySof MA30 intraocular lens (Alcon Laboratories, Ft Worth, Tex) (gr...

Fibroblast growth factor-8 (FGF-8) is an important signaling molecule in the generation and patterning of the midbrain, tooth, and limb. In this study we show that it is also involved in eye development. In the chick, Fgf-8 transcripts first appear in the distal optic vesicle when it contacts the head ectoderm. Subsequently Fgf-8 expression increases and becomes localized to the central area of...

It is known that when hyperopic or myopic defocus is imposed on chick eyes by spectacle lenses, they rapidly compensate, becoming myopic or hyperopic respectively, by altering the depth of their vitreous chamber. Changes in two components--ocular length and choroidal thickness--underlie this rapid compensation. With monocular lens treatment, hyperopic defocus imposed by negative lenses resulted...

PURPOSE To determine the sources of binocular visual field loss most strongly associated with falls in a cohort of older women. METHODS In the Study of Osteoporotic Fractures, women with severe binocular visual field loss had an increased risk of two or more falls during the 12 months following the eye examination. The lens and fundus photographs of the 422 women with severe binocular visual ...

After optic nerve injury in mature mammals, retinal ganglion cells (RGCs) are normally unable to regenerate their axons and undergo delayed apoptosis. However, if the lens is damaged at the time of nerve injury, many RGCs survive axotomy and regenerate their axons into the distal optic nerve. Lens injury induces macrophage activation, and we show here that factors secreted by macrophages stimul...

Mouse embryos, homozygous for the small eye (Sey) mutation die soon after birth with severe facial abnormalities that result from the failure of the eyes and nasal cavities to develop. Mutations in the Pax6 gene are responsible for the Sey phenotype. As a general disruption of eye and nasal development occurs in the homozygous Sey embryos, it is unclear, from the mutant phenotype alone, which t...

Throughout the fiber optics industry, one is constantly hearing that without substantial improvements in production efficiency, new markets for fiber optic technology will remain elusive. It is therefore a common goal throughout the fiber optics industry to continually improve production processes. We propose a scalable improvement for a production step found in a wide range of fiber optic comp...

A case of morning glory syndrome with striking persistence of primary vitreous is presented. The hypothesis that the syndrome is an expression of abnormal closure of the embryonic fissure is substantiated by the coexistence of lens colobomas. Furthermore, the marked primary vitreous hyperplasia shows the way in which persistence of primary vitreous influences the clinical expression with respec...

We demonstrate serial-to-parallel conversion of 40 Gbps optical time division multiplexed (OTDM) signal to 4x10 Gbps wavelength divisionmultiplexed (WDM) individual channels by using Optical Fourier Transformation (OFT) method. OFT is also called time lens technique and it is implemented by the combination of dispersive fiber and phase modulation. In this research, electro-optic phase modulator...