Optical coherence tomography (OCT) has revolutionized ophthalmic diagnosis as a non-invasive, cross-sectional imaging technique in the last 30 years and hence is one of fastest adopted advanced technologies history medicine. A miniaturization OCT devices would not only reduce size but ideally also costs therefore create potential new markets. systems based on photonic integrated circuits (PIC) ...

Commercially available high-resolution three-dimensional optical imaging modalities-including confocal microscopy, two-photon microscopy, and optical coherence tomography-have fundamentally impacted biomedicine. Unfortunately, such tools cannot penetrate biological tissue deeper than the optical transport mean free path (approximately 1 mm in the skin). Photoacoustic tomography, which combines ...

We present a photoacoustic tomography-guided diffuse optical tomography approach using a hand-held probe for detection and characterization of deeply-seated targets embedded in a turbid medium. Diffuse optical tomography guided by coregistered ultrasound, MRI, and x ray has demonstrated a great clinical potential to overcome lesion location uncertainty and to improve light quantification accura...

background:  optical coherence tomography (oct) is a non-invasive instrument, which can be used to estimate the thickness of the retinal nerve fibre layer (rnfl) and provides an indirect measurement of axonal destruction in multiple sclerosis (ms). the main aim of this study was to find out any correlations between p100 latency in visual evoked potential (vep) and rnfl thickness. methods: the p...

purpose: to describe the association between optic disc traction and non-arteritic anterior ischemic optic neuropathy (naion). methods: eighty three eyes of 83 patients with naion were evaluated by optical coherence tomography (oct) for detecting vitreous adhesion to the optic nerve head with separation from adjacent retina (partial posterior vitreous detachment). those who were negative for su...

Full-field optical coherence tomography (FF-OCT) is a recent optical imaging technology based on low-coherence interference microscopy for imaging of semi-transparent samples with ~1 μm spatial resolution. FF-OCT produces en-face tomographic images obtained by arithmetic combination of interferometric images acquired by an array camera. In this paper, we demonstrate a unique multimodal FF-OCT s...

PURPOSE We evaluated the feasibility of using optical coherence tomography and optical coherence microscopy technology to assess human kidney morphology. MATERIALS AND METHODS A total of 35 renal specimens from 19 patients, consisting of 12 normal tissues and 23 tumors (16 clear cell renal cell carcinomas, 5 papillary renal cell carcinomas and 2 oncocytomas) were imaged ex vivo after surgical...