BACKGROUND Vesicoureteric reflux (VUR) is the retrograde flow of urine from the bladder into the ureters. It is the most common urological anomaly in children, and a major cause of end-stage renal failure and hypertension in both children and adults. VUR is seen in approximately 1-2% of Caucasian newborns and is frequently familial. OBJECTIVE AND METHODS In order to search for genetic loci in...

BACKGROUND This study assessed the barriers to sight impairment certification in the East London Borough of Tower Hamlets amongst patients attending the Diabetic Retinopathy Screening Service (DRSS). METHODS All patients who attended DRSS between 1stApril 2009 and 31st of March 2010 and whose recorded best corrected visual acuity (BCVA) at DRSS fulfilled the requirements for sight impairment ...

Pig scrotal/inguinal and umbilical hernias are the most prevalent congenital disorders in pigs and often cause animal welfare problems and economic loss. To identify susceptibility loci for these traits, a genome-wide scan with 194 microsatellite markers covering the pig genome was performed in a White Duroc x Erhualian resource population with 23 scrotal/inguinal F(2) animals, 50 umbilical F(2...

p97 (CDC-48 in Caenorhabditis elegans) is a ubiquitin-selective AAA (ATPases associated with diverse cellular activities) chaperone and its key function is to disassemble protein complexes. p97 functions in diverse cellular processes including endoplasmic reticulum (ER)-associated degradation, membrane fusion, and meiotic and mitotic progression. However, its cellular functions in development h...

Physikalisch-Technische Bundesanstalt, Abteilung Optik, Photometrie, Postfach 33 45, 38023 Braunschweig, Germany A trilateral intercomparison of photometric units between NIST (USA), NPL (UK), and PTB (Germany) has been conducted to update the knowledge of the relationship between the photometric units disseminated in the three countries. The luminous intensity unit (cd), the luminous responsiv...

An extensive programme was successfully carried out during the 1995 to 1998 NMS programme to recalibrate and model by Monte Carlo simulations the characteristics of two NPL long counters that are routinely used to standardise neutron fluences [Ta98,Ta00] for neutron energies above 500 keV. The present work is a continuation of it in that the counters responses and effective centres have been me...

Essentially, the bank is financial institution which has function to raise funds from thecommunity in form of deposits, and channel it back community creditor other. Credits main activities performed by Bank Perkreditan Rakyat, because will bemakes a profit. However, presenting credits also provide lot risks that must bereceived or experienced BPR, be received aresourced credit. Therefore, this...

Nonradiative energy transfer (NRET) has been extensively studied in colloidal nanocrystal (quantum dots) and nanorod (quantum wires) assemblies. In this work, we present the first account of spectroscopic evidence of NRET in solid thin films of CdSe based colloidal nanoplatelets (NPLs), also known as colloidal quantum wells. The NRET was investigated as a function of the concentration of two NP...

AIM To evaluate whether the T1D susceptibility locus on chromosome 16q contributes to the genetic susceptibility to T1D in Russian patients. METHOD Thirteen microsatellite markers, spanning a 47-centimorgan genomic region on 16q22-q24 were evaluated for linkage to T1D in 98 Russian multiplex families. Multipoint logarithm of odds (LOD) ratio (MLS) and nonparametric LOD (NPL) values were compu...

PURPOSE Myopia is the most common human eye disorder with complex genetic and environmental causes. To date, several myopia loci have been identified in families of different geographic origin. However, no causative gene(s) have yet been identified. The aim of this study was the characterization of Polish families with high-grade myopia, including genetic analysis. METHODS Forty-two multiplex...