Oral sedatives are often required for children who require dental restoration. Most children are able to receive this in the dental office, often using nitrous oxide with minimal sedation to facilitate the procedure. However, there are children who will not cooperate during the examination process or during the actual dental procedure without sedation [1]. This can be due to young age, behavior...

conclusions midazolam could be used as a safe and effective drug for conscious sedation, general anaesthetic premedication and the treatment of seizures during dental treatment. however, further research on paediatric patients would be beneficial. evidence acquisition to conduct this review of the literature, pub-med and scopus were searched using the following terms: midazolam, oral, transmuco...

PURPOSE This study was designed to examine the efficacy and safety of submucosal (SM) midazolam and oral chloral hydrate (CH) when used for pediatric conscious sedation in a clinical dental environment. METHODS Twenty children ages 32 to 63 months participated in this institutionally approved study. Selection criteria included good health (ASA I), 2 to 5 years of age, uncooperative behavior, ...

Physically and neurologically handicapped pediatric dental patients are often a challenge to treat and may require the use of pharmacological agents for behavior modification. The purpose of this study was to investigate the safety, in terms of vital sign changes and complications, and the effectiveness, in terms of behavioral changes, of two dosages of oral midazolam as a conscious sedative ag...

Aim This retrospective observational study evaluates the safety and efficacy of intravenous sedation using midazolam only or combinations two three drugs including propofol alfentanil for complex dental surgery such as implant placement sinus augmentations. Methods The analyses 60 patients aged 42–79 who required advanced techniques oral procedures. Twenty had (M), 10 a 2-drug combination (MP) ...

Little is known about whether midazolam sedation can reduce salivary cortisol levels and consequently influence children's behaviour during dental treatment. The aim of this study was to evaluate the effect of midazolam sedation on salivary cortisol and its correlation with children's behaviour during restorative dental treatment. Eighteen healthy children, aged two to five years, were randomly...

BACKGROUND Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alpha(2) selective drug with more favorable pharmacokinetic properties than cloni...