BACKGROUND The goal of this study was to identify the in vivo effects in patients with hyposalivation of a novel slowly dissolving adhering test disc upon on enamel remineralization, oral biofilm, salivary production, pH and buffering, gingival health, and on self-evaluation of oral well-being. METHODS Five subjects with xerostomia wore custom made retainers carrying 5 demineralized enamel ch...

We have previously shown that antigen-induced eosinophil recruitment into the tissue of sensitized mice is mediated by CD4+ T cells and IL-5. To determine whether the induction of oral tolerance down-regulates antigen-induced eosinophil recruitment into the tissue, we studied the effect of oral administration of a protein antigen on antigen-induced eosinophil infiltration in the trachea of sens...

AIMS Chewing of betel quid (BQ) increases the risk of oral cancer and oral submucous fibrosis (OSF), possibly by BQ-induced toxicity and induction of inflammatory response in oral mucosa. METHODS Primary gingival keratinocytes (GK cells) were exposed to areca nut (AN) components with/without inhibitors. Cytotoxicity was measured by 3-(4,5-dimethyl- thiazol- 2-yl)-2,5-diphenyl-tetrazolium brom...

The aim of this study was to evaluate the link between Candida albicans growth and dimorphism and the production of keratins by oral epithelial cells. Various culture models (monolayer and non-keratinized and keratinized engineered human oral mucosa) were produced and used for this purpose. Cell morphology, tissue structure, and the transition of C. albicans were assessed following cell and tis...

background and aims. a correct diagnosis is the most important step in the treatment of oral lesions and each oral lesion has specific clinical features that provide clinical diagnosis; however, some of these features are common among different lesions. in these situations, biopsy and histopathological examination are indicated. the aim of this study was to evaluate the relationship between cli...

introduction the frequency of pediatric and adolescent oral and maxillofacial lesions is various in different societies. the present study aimed at investigating the frequency of oral and maxillofacial pediatric and adolescent biopsies in zahedan (southeast iran), and compare the results with other epidemiologic studies.methods and materials this retrospective study reviewed oral and maxillofac...

Background Oral mucositis is an adverse effect of chemotherapy. Type of chemotherapy regimen is the most important factor causing mucositis. Oral mucositis is usually associated with transient decrease in saliva production. The goal was to study effects of gum consumption on oral mucositis in children undergoing chemotherapy. Materials and Methods This randomized c...

A longitudinal study of oral and written naming and comprehension of nouns and verbs in an individual (M. M. L.) with nonfluent primary progressive aphasia (PPA) is reported. M. M. L. showed progressive deterioration of oral naming of verbs well before deterioration of written naming of verbs and before deterioration of oral or written naming of nouns. Her comprehension of both nouns and verbs ...