Diabetes mellitus (DM) refers to a group of common metabolic disorders that share the phenotype of hyperglycemia. Several distinct types of DM are caused by a complex interaction of genetics and environmental factors. Depending on the etiology of the DM, factors contributing to hyperglycemia include reduced insulin secretion, decreased glucose utilization, and increased glucose production. The ...

One hundred and seven profundaplasties have been performed for rest pain or gangrene due to advanced arterial degeneration below the inguinal ligament. Local anaesthesia was used for 78 operations. There were 19 early failures (2 deaths and 17 amputations) and 16 later amputations. During 4'5 years of followup, 25 other patients have died. The results for diabetic gangrene were worse than for o...

Background and Objectives: The primary objective of this study was to investigate the incidence lower extremity amputations (LEAs) in a representative population from Romania, both diabetic non-diabetic adults, including trauma-related amputations. secondary evaluate trends LEAs overall ratio major-to-minor Material Methods: retrospective included data Romanian National Hospital Discharge Recor...

Amputation of a limb may have a negative impact on the psychological and physical well-being, mobility and social life of individuals with limb amputations. Participation in sports and/or regular physical activity has a positive effect on the above mentioned areas in able-bodied individuals. Data concerning participation in sports or regular physical activity together with its benefits and risk...

Symmetrical peripheral gangrene (SPG) is an uncommon but devastating complication in critically ill patients with a high mortality. It is seen in a wide variety of medical conditions, presenting as symmetrical gangrene of two or more extremities without large vessel obstruction. We hereby report a 65-year-old woman diagnosed of having E. coli bacteremia with urosepsis, who presented with acute ...

Diabetes mellitus is the most common endocrine disease. It comprises a heterogeneous group of hyperglycemic disorders characterized by high serum glucose concentration and disturbances of carbohydrate and lipid metabolism. Acute complications include hypoglycemia, diabetic ketoacidosis (DKA), and hyperglycemic hyperosmolar state (HHS). Long-term complications affect multiple organ systems throu...