Potent cannabinoid CB1 receptor ligands include anandamide [N-(2-hydroxyethyl)arachidonamide], Delta9-tetrahydrocannabinol, and 3H-CP 55,940 at the agonist site and selected organophosphorus esters (including some pesticides) and organosulfur compounds at a proposed closely coupled "nucleophilic" site. This study considers the toxicological and structural features of alkylfluorophosphonates, be...

Arylthiols were reacted with acrylonitrile under basic conditions to form the corresponding aryl sulfides which oxidised sodium metaperiodate in aqueous methanol yield 3-arylsulphinylpropanenitriles that upon thermolysis refluxing toluene produced a mixture of diarylthiosulfonates and diaryldisulfides. The two products was easily separated by flash chromatography characterized spectroscopically...

Reactive molecular dynamics simulations were used to investigate reactions between di- tert -butyl disulfide and ferrous surfaces. Tribochemical characterized with without a model base oil, n -dodecane, on either Fe(100) or H-passivated Fe 2 O 3 Reaction yield increased both temperature pressure for all systems. The presence of the oil did not significantly affect reaction pathway, but impeded ...

Phytochemicals are dietary compounds considered lifespan-essentials. Their beneficial effects strongly depend on their bioaccessible quantities, in turn determined by food matrix components. Organosulfur (OSCs) renowned phytochemicals responsible for garlic health-effects. Currently, role OSCs bioaccessibility has not been studied. Furthermore, the digestive behavior of isolated added to prepar...