Insights into the molecular mechanisms underlying neural development in vertebrates come from the cloning and the functional analysis of genes which are involved in the molecular pathways leading to neural induction, tissue specification and regionalization of the brain. Among them, transcription factors belonging to the orthodenticle family (Otx1, Otx2) play an important role during early and ...

Eyes are the preeminent source of sensory information for the brain in most species, and many features of eyes reflect evolutionary solutions to particular selective pressures, both from the nonbiological environment and from other animals. As a result, the evolution of eyes, among all the sense organs, has attracted considerable attention from scientists. Paired eyes in the three major phyla, ...

Tissue engineering is an exciting new area of medicine with rapid growth and expansion over the last decade. It has the potential to have a profound impact on the practice of medicine and influence the economic development in the industry of biotechnology. In almost every specialty of medicine, the ability to generate replacement cells and develop tissues will change the focus from artificial o...

The retinal circulation of the normal human retinal vasculature is statistically self-similar and fractal. Studies from several groups present strong evidence that the fractal dimension of the blood vessels in the normal human retina is approximately 1.7. This is the same fractal dimension that is found for a diffusion-limited growth process, and it may have implications for the embryological d...

In Nature, the intrinsic cooperation between organism’s parts is capital. Most living systems are composed of organs, functional units specialized for specific actions. In our last research, we developed an evolutionary model able to generate artificial organs. This paper deals with the assembly of organs. We show, through experimentation, the development of an artificial organism composed of f...

The development of information technology from year to always experiences very rapid development, and one the positive impacts this is existence innovation in field education. Education today already uses technology, especially augmented reality (AR). purpose study help high school students getting know human internal external organs through 2D or 3D virtual objects projected against real world...

The goal of sex assignment is to facilitate the best possible quality of life for the patient. Factors such as reproductive system development, sexual identity, sexual function, and fertility are important considerations in this regard. Although some DSD gender assignments are relatively straightforward, those with midstage genital ambiguity and unclear gonadal function represent a major challe...

a hydatid cyst is a zoonotic infection caused by the larval forms of mostly the echinococcus granulosus. in humans, the most common site of cyst development is the liver (60%), followed by the lungs (20%), and much less commonly in other organs such as kidney, spleen, brain, and other soft tissues. the localization of cysts in muscles and subcutaneous is very rare. we report a case of 38-year-o...

Endoreduplication is an alternative cell cycle that omits cell division such that cellular ploidy increases, generating “endopolyploidy”. Endoreduplication is common among eukaryotes and is thought to be important in generalized cell differentiation. Previous research on ants suggests that they endoreduplicate in body segment-dependent manners. In this study, we measured endopolyploidy of spe...