Abstract Cleft births surveillance is essential in healthcare and prevention planning. Data are needed precision medicine to target upstream management for at-risk individuals. This study characterizes Singapore’s population-based orofacial cleft topography by ethnicity gender, establishes the cohort’s infant mortality rate. Data, decade 2003 2012, were extracted National Birth Defects Registry...

BACKGROUND Few epidemiological studies have explored the relationship between orofacial clefts and bronchodilators. We assessed whether mothers who used bronchodilators during early pregnancy were at an increased risk of delivering infants with orofacial clefts. METHODS We used National Birth Defects Prevention Study case-control data from mothers of 2711 infants with orofacial clefts and 648...

Clefts of lip and palate are the most common congenital deformities involving the orofacial region. One of the immediate problems to be addressed in newborn is difficulty in feeding. Here, we present a case of 4month old infant with unilateral cleft lip and palate for whom feeding appliance was made.

OBJECTIVE Cleft lip with or without cleft palate (CL±P) or cleft palate (CP) are groups of malformations named orofacial clefts (OC), which are the second leading cause of birth defects. This study aimed to analyze clinical and epidemiological features of Brazilian patients with OC, studying cases treated in the reference center of the state of Paraná (PR). METHODS 2,356 charts were reviewed ...

  Background: Several studies have examined the effects of folic acid fortification on the occurrence of orofacial clefts. This study was carried out to evaluate the impact of flour fortification with folic acid on oral clefts in Northern Iran.   Methods : In this hospital based study from March 2006 to September 2009, we screened the total number of live births at all hospitals in Golestan pro...

background oral cleft is the most common orofacial congenital anomaly among live births. this anomaly at birth is one of the main causes of children disability and mortality.  congenital heart disease (chd) is one of the most common anomalies in oral clefts.  this study aimed to assess the incidence of congenital heart diseases anomalies in newborns with oral clefts. materials and methods this ...