Bévengut, Michelle, François Clarac, and Daniel Cattaert. Antithe periphery in the sensory axons (El Manira et al 1991b). dromic modulation of a proprioceptor sensory discharge in crayfish. These spikes have no postsynaptic effect centrally (Cattaert J. Neurophysiol. 78: 1180–1183, 1997. In the proprioceptive neuet al. 1994; El Manira et al 1991b) but their peripheral rons of the coxo-basal cho...

Sensory conduction velocity of the sural nerve was measured in 50 normal subjects and 100 consecutive patients with suspected or established diagnosis of peripheral neuropathy. The sensory action potential was recorded by the orthodromic technique for the distal and the proximal segments. In the patient group, sensory conduction of the proximal segment appeared to be more consistent and easier ...

This patient has an arrhythmia with orthodromic circus movement tachycardia and dual AV-nodal pathways. In addition, the ECG shows a Brugada pattern. The resting ECG (Fig. 1a) shows sinus rhythm and a type 2 Brugada pattern. The 12-lead ECG during arrhythmia (Fig. 1b) shows a narrow QRS rhythm, 88 bpm (cycle length: 680 ms) with a 1:1 AV ratio. The P waves are narrow and inverted in leads II, I...

Tiagabine is a potent GABA uptake inhibitor with demonstrated anticonvulsant activity. GABA uptake inhibitors are believed to produce their anticonvulsant effects by prolonging the postsynaptic actions of GABA, released during episodes of neuronal hyperexcitability. However, tiagabine has recently been reported to facilitate the depolarizing actions of GABA in the CNS of adult rats following th...

A 36 year-old man with Wolff Parkinson White syndrome due to a left-sided accessory pathway (AP) was referred for catheter ablation. Whether abolition of antegrade and retrograde AP conduction during ablation therapy occurs simultaneously, is unclear. At the ablation procedure, radiofrequency delivery resulted in loss of preexcitation followed by a short run of orthodromic tachycardia with ecce...