نتایج جستجو برای: overactive bladder syndrome

تعداد نتایج: 675415  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2010
Wouter Everaerts Xiaoguang Zhen Debapriya Ghosh Joris Vriens Thomas Gevaert James P Gilbert Neil J Hayward Colleen R McNamara Fenqin Xue Magdalene M Moran Timothy Strassmaier Eda Uykal Grzegorz Owsianik Rudi Vennekens Dirk De Ridder Bernd Nilius Christopher M Fanger Thomas Voets

Reduced functional bladder capacity and concomitant increased micturition frequency (pollakisuria) are common lower urinary tract symptoms associated with conditions such as cystitis, prostatic hyperplasia, neurological disease, and overactive bladder syndrome. These symptoms can profoundly affect the quality of life of afflicted individuals, but available pharmacological treatments are often u...

2012
Wooseuk Sung Hyunwook You Tai Young Yoon Sun-Ju Lee

PURPOSE We quantified and described the economic burden of overactive bladder and stress urinary incontinence in Korea. We calculated direct costs by identifying public and private data sources that contain population-based data on resource utilization by patients with stress urinary incontinence and overactive bladder. METHODS For estimating indirect costs (productivity loss), the human capi...

2012
Jacques Corcos

Overactive bladder (OAB) is a common problem whose prevalence increases with advancing age and compromises ­health-related­quality­of­life.­Tolterodine­was­the­first­antimuscarinic­drug­specifically­designed­to­treat­OAB. Through­MEDLINE,­we­reviewed­articles,­standardization­reports­and­meeting­abstracts,­published­between­2001­and­2011,­on­the­efficacy and tolerability of Tolterodine extended...

Journal: :American journal of obstetrics and gynecology 2012
Peter K Sand G Willy Davila Vincent R Lucente Heather Thomas Kim E Caramelli Gary Hoel

OBJECTIVE This subgroup analysis of a phase-3 study evaluated the efficacy and safety of oxybutynin chloride topical gel (OTG) in women with overactive bladder syndrome (OAB). STUDY DESIGN Women (n = 704) with urgency-predominant urinary incontinence received OTG or placebo for 12 weeks. The primary endpoint was change from baseline to last observation in number of daily incontinence episodes...

Journal: :Reviews in urology 2002
Grannum R Sant

Interstitial cystitis (IC) is a bladder syndrome of unknown etiology. The cause of IC is most likely multifactorial and includes genetic and environmental factors. Various pathophysiological changes in the bladder, pelvis, and peripheral and central nervous systems have been identified, and this has led to the emergence of biologically specific treatment modalities. Interstitial cystitis is bei...

Journal: :The Journal of urology 2014
Yao-Chi Chuang Jonathan H Kaufmann David D Chancellor Michael B Chancellor Hann-Chorng Kuo

PURPOSE Cystoscopic intradetrusor injection of botulinum toxin has helped patients with refractory overactive bladder but with the increased risks of urinary tract infection and urinary retention. We assessed whether catheter instillation of 200 U onabotulinumtoxinA formulated with liposomes is safe and effective for the treatment of overactive bladder. MATERIALS AND METHODS This 2-center, do...

2009
Khanh Tran Robert M. Levin Shaker A. Mousa

Overactive bladder syndrome (OAB) refers to individuals with the following symptoms: urinary urgency, increased urinary frequency, and urge incontinence. These symptoms are not life threatening but can cause embarrassment and significantly impact quality of life. There are numerous treatment options for OAB, including behavioral therapy, traditional pharmacological therapy or a combination of t...

Journal: :International braz j urol : official journal of the Brazilian Society of Urology 2014
Juan Pablo Valdevenito Ann Leonard Clive J Griffiths Robert Pickard Christopher Harding

OBJECTIVES To determine whether there are differences in pressure and flow measurements between conventional cystometry (CONV) and ambulatory urodynamic monitoring (AMB) in women with overactive bladder syndrome and urinary incontinence. MATERIALS AND METHODS Retrospective study which included female subjects who underwent both CONV (with saline filling medium) and AMB, separated by less than...

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