Mathematics Applications Consortium for Science and Industry, Department of Mathematics and Statistics, University of Limerick, Limerick, Ireland; Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115; Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford OX2 6GG, United Kingdom; CABDyN Complexity Centre, Saïd Busines...

From the Oxford Centre for Diabetes, Endocrinology and Metabolism; the Oxford National Institute of Health Research Biomedical Research Centre; and the Wellcome Trust Centre for Human Genetics, University of Oxford — all in Oxford, United Kingdom. Address reprint requests to Dr. McCarthy at the Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Oxford OX3 7LJ, Unit...

Dept of Physiology, Anatomy and Genetics, University of Oxford; University of Oxford Centre for Clinical Magnetic Resonance Research (OCMR); Dept of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK; St.Vincent’s Hospital, Darlinghurst, Sydney, Australia; Oxford NIHR Biomedical Research Centre, University of Oxford; Centre for Statistics in Medicine, Wolfson College Annexe, Universit...

BACKGROUND AND OBJECTIVES Megalin is highly expressed at the apical membranes of proximal tubular epithelial cells. A urinary full-length megalin (C-megalin) assay is linked to the severity of diabetic nephropathy in type 2 diabetes. This study examined the relationship between levels of urinary C-megalin and histological findings in adult patients with IgA nephropathy (IgAN). DESIGN, SETTING...

1Department of Statistics, 1 South Parks Road, University of Oxford, Oxford OX1 3TG, UK 2Institute for Emerging Infections, The Oxford Martin School, Oxford OX1 3BD, UK 3Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford OX3 7BN, UK 4Department of Paediatrics, University of Oxford, Oxford OX1 3SY, UK 5Nuffield Department of Clinical Medicine, Peter Medawar Building for Pathogen R...

Interlanguage pragmatics (ILP) has witnessed a growing body of research in the past two decades. One of the under-explored domains of L2 pragmatics is the role of learning strategies specifically tailored for the development of ILP knowledge. Therefore, this investigation aimed to determine the significant interlanguage pragmatic learning strategies (IPLS) used by high vs. low L2 pragmatic achi...

1Stem Cell Research Laboratory, National Health Service Blood and Transplant, John Radcliffe Hospital, Oxford, United Kingdom; 2Nuffield Department of Clinical Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom; 3MRC Molecular Haematology Unit, Weatherall Institute for Molecular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, United Kingd...

Sang Hoon Lee,1, ∗ Mark D. Fricker,2, 3 and Mason A. Porter4, 3 1Oxford Centre for Industrial and Applied Mathematics, Mathematical Institute, University of Oxford, Oxford OX2 6GG, United Kingdom 2Department of Plant Sciences, University of Oxford, South Parks Road, Oxford OX1 3RB, United Kingdom 3CABDyN Complexity Centre, University of Oxford, Oxford OX1 1HP, United Kingdom 4Oxford Centre for ...

The 2009 Oxford Classification of immunoglobulin A (IgA) nephropathy (IgAN) identifies four histological features as predictors of renal prognosis: mesangial hypercellularity (M), endocapillary hypercellularity (E), segmental glomerulosclerosis (S), and tubular atrophy/interstitial fibrosis (T). However, the clinical and prognostic significance of crescent formation still remains controversial....

Dear Editor-in-Chief, I read with great interest the recently published article by Nasri H. entitled “IgG deposition in IgA nephropathy patients” in the esteemed Journal of Renal Injury Prevention. In this study on 114 biopsies of IgA nephropathy (IgAN) patients they found no significant association of IgG deposits with age. There was no correlation of IgG deposit with four morphologic variable...