نتایج جستجو برای: oxidized low density lipoprotein ox

تعداد نتایج: 1546476  

Journal: :European heart journal 2014
Georg Daniel Duerr Matthias Endlich Jan-Malte Sinning Bahman Esmailzadeh Nikos Werner Fritz Mellert

Breslow JL. Severe hypercholesterolemia and atherosclerosis in apolipoprotein Edeficient mice created by homologous recombination in ES cells. Cell 1992;71:343–353. 19. Imanishi T, Hano T, Sawamura T, Takarada S, Nishio I. Oxidized low density lipoprotein potentiation of Fas-induced apoptosis through lectin-like oxidized-low density lipoprotein receptor-1 in human umbilical vascular endothelial...

Journal: :Molecular pharmacology 2012
Sara Matarazzo Maria Chiara Quitadamo Ruggiero Mango Sarah Ciccone Giuseppe Novelli Silvia Biocca

Lectin-like oxidized low-density lipoprotein (LOX-1), the primary receptor for oxidized low-density lipoprotein (ox-LDL) in endothelial cells, is up-regulated in atherosclerotic lesions. Statins are the principal therapeutic agents for cardiovascular diseases and are known to down-regulate LOX-1 expression. Whether the effect on the LOX-1 receptor is related to statin-mediated cholesterol-lower...

Journal: :iranian journal of neurology 0
alia saberi poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran. hamid reza hatamian poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran ehsan kazemnejad poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran nasim ghorbannejad poursina hospital, department of neurology, guilan university of medical sciences, rasht, iran

background: some coincidental disorders with migraine have been introduced that may have role in its pathogenesis or aggravation. in this study we determined the relative frequency of hyperlipidemia as a coincidental disorder in patients affected by migraine. methods: a total of 102 migraine-affected patients according to international headache society (his) criteria and 103 control subjects ad...

2017
Yasumi Uchida

PURPOSE OF REVIEW In vivo imaging of the native substances, including lipoproteins, that comprise human atherosclerotic plaques is currently beyond the scope of any available imaging techniques. Color and near-infrared fluorescent angioscopy (CFA and NIRFA, respectively) systems have been recently developed for molecular imaging of lipoproteins within the human coronary arterial wall ex vivo an...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2001
M Minami N Kume T Shimaoka H Kataoka K Hayashida Y Akiyama I Nagata K Ando M Nobuyoshi M Hanyuu M Komeda S Yonehara T Kita

Receptor-mediated endocytosis of oxidized low density lipoprotein (Ox-LDL) by macrophages and the subsequent foam cell transformation in the arterial intima are key events in early atherogenesis. Recently, we have identified a novel macrophage cell-surface receptor for Ox-LDL by expression cloning from a cDNA library of phorbol 12-myristate 13-acetate-stimulated THP-1 cells, designated as the s...

2003
Hidemi Ishii Tsuyoshi Tezuka Hiroyuki Ishikawa Kimihiko Takada Koji Oida Shuichi Horie

The present work investigated the mechanism for down-regulation of thrombomodulin (TM), an anticoagulant glycoprotein, on cultured umbilical vein endothelial cells (HUVECs) exposed to lipid extracts from oxidized low-density lipoprotein (oxLDL). HUVECs exposed to phospholipid extracts, but not to free cholesterol, triglyceride, or cholesterol ester, isolated from ox-LDL reduced TM mRNA levels t...

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