There is some anecdotal evidence that oxygen-ozone therapy may be beneficial in some human diseases. However so far only a few biochemical and pharmacodynamic mechanisms have been elucidated. On the basis of preliminary data we postulated that controlled ozone administration would promote an oxidative preconditioning preventing the hepatocellular damage mediated by free radicals. Six groups of ...

Equipment has been developed for the servo-control of arterial oxygen tension in sick, newborn babies. Using an indwelling umbilical arterial oxygen electrode as sensor, the equipment successfully regulated the administration of oxygen to 12 newborn babies with respiratory distress syndrome, significantly improving the stability of arterial oxygen tension and lessening the duration of episodes ...

introduction: hospital has a complex and special structure and the important question that hospital management facing with is how technology can change structure. in the near future, no factor like it is able to change the structure of organization. this research is a way to know the effect of it on triple dimensions of organization structure includes complexity, formalization, and centralizati...

experimental and epidemiological evidences implicate the involvement of oxygen derived radicals in the pathogenesis of cancer development. oxygen derived radicals are able to cause damage to membranes, mitochondria and macromolecules including proteins, lipids and dna. accumulation of dna damages has been suggested to contribute to carcinogenesis. it would, therefore, be advantageous to pinpoin...

In the first series of experiments, preretinal oxygen tensions were measured using microelectrodes in newborn kittens, at 6 +/- 2 days of age, following their placement in an atmosphere of 80 to 90% oxygen for 5 +/- 1 day. The oxygen exposure caused an obliteration of the normally developing retinal vasculature. Preretinal oxygen tensions in the resultant avascular retina were close to zero whi...

During the last few years there has been growing concern that chronic pulmonary oxygen toxicity might result from the administration of high concentrations of oxygen with intermittent positive pressure ventilation (IPPV) during the management of respiratory failure. This concern was fostered by Nash, Blennerhassett and Pontoppidan (1967) who reported an association between the duration and conc...

Nerve conduction velocity has been studied in the ulnar nerve of human subjects before and during anaesthesia. No significant changes in velocity were observed following the administration of thiopentone, nitrous oxide, oxygen and halothane in normal clinical quantities. A transient increase in nerve conduction velocity was noted following the administration of paralytic doses of gallamine trie...

background pain management with the use of sedatives and analgesics has several advantages and few complications or side effects. objectives in this study, we planned to evaluate the effects of pain control on oxygen saturation independent of other factors, such previous cardio-pulmonary conditions or respiratory rate. patients and methods sixty-seven adult patients with direct trauma to extrem...

A study of the estimated hepatic blood flow (EHBF) using a colloidal gold technique in 28 patients undergoing saphenous vein stripping, showed that the EHBF decreased to 68% of its initial value during the period of halothane anaeshtesia and operation. When enteral oxygen was added EHBF increased to 82% of its initial value. An investigation in 14 other patients under going upper abdominal oper...

The effects of intravenous N-acetylcysteine on hepatic and systemic haemodynamics were investigated in 11 patients with stable cirrhosis (eight alcohol; two primary biliary cirrhosis; one cryptogenic). N-acetylcysteine administration had no effect on the mean heart rate or mean arterial blood pressure despite a significant fall in systemic and pulmonary vascular resistance. Cardiac index increa...