Human spermatozoa generate low levels of reactive oxygen species in order to stimulate key events, such as tyrosine phosphorylation, associated with sperm capacitation. However, if the generation of these potentially pernicious oxygen metabolites becomes elevated for any reason, spermatozoa possess a limited capacity to protect themselves from oxidative stress. As a consequence, exposure of hum...

We used quantitative genetics to test a controversial theory of heat stress, in which animals overheat when the demand for oxygen exceeds the supply. This theory, referred to as oxygen- and capacity-limited thermal tolerance, predicts a positive genetic correlation between hypoxia tolerance and heat tolerance. We demonstrate the first genetic correlation of this kind in a model organism, Drosop...

In order to study the interaction of glutathione, vitamin C and vitamin E under hyperoxia (95 % oxygen) and hyperbaric oxygen (2.5 atmospheric pressure), 20 days old male Guinea pigs were fed with basal vitamin C free diet, while receiving a vitamin C supplement of either high concentration (50 mg/day) or low concentration (1 mg/day) for two weeks. Animals were than exposed to hyperoxia and hyp...

In the present study, different oxygen levels were examined in two weight groups of great sturgeon Huso huso including small size (with initial weight 280.9 ± 49.2 g) and large size (with initial weight 1217.9 ± 138.1 g). The fish were kept in hypoxia (2-3 mg/l), normoxia (5-6 mg/l) and hyperoxia (9-10 mg/l) conditions for 8 weeks and then were individually placed in the tanks with oxygen lev...

The two vital respiratory parameters namely Oxygen consumption of the whole fish and Opercular activity in Indian Major Carp was investigated during thermal-stress Thermal-adaptation. major carp Catla catla subjected to Slow temperature change from 22 ⁰c 32⁰c (heat-adaptation) (cold -adaptation) at rate 1⁰c ̷ 60 hours showed a gradual stepping-up oxygen opercular heat-adaptation stepping-down ca...

The groundbreaking work of Dr Ola Saugstad and colleagues 1, 2 led to a reappraisal and more judicious use of oxygen in term infants. Of course, this led to questioning the appropriate fraction of inspired oxygen (FIO2) to use in the initial resuscitation of preterm infants. Preterm infants are particularly vulnerable to free radical–associated conditions and oxidative stress; the use of high o...

Objectives: The primary purpose of this study was to determine the methods and means of prevention and treatment of coronary artery disease. In this study, we used a new regimen on heart rate and functional capacity of patients after myocardial infarction. This study also determines the effect of a new regimen on these factors. Methods: The cross sectional study was designed to assess the clin...

Oxidative stress is an imbalance between cellular production of reactive oxygen species and the counteracting antioxidant mechanisms. The brain with its high oxygen consumption and a lipid-rich environment is considered highly susceptible to oxidative stress or redox imbalances. Therefore, the fact that oxidative stress is implicated in several mental disorders including depression, anxiety dis...

abstract diabetes mellitus is one of the major metabolic disorders. diabetes is recognized for severe complications including diabetic nephropathy, neuropathy and retinopathy. long-lasting effect of hyperglycemia results in increased oxidative stress. oxidative stress results from an imbalance between radical-generating and radical scavenging systems. increased oxidative stress has been shown t...